Trivia: Known mostly for his role as medical intern John "J.D." Dorian on NBC's sitcom Scrubs, Zach Braff has an enthusiasm for acting that can be traced back to his childhood in South Orange, NJ, where, at eight years old, he recalls watching his attorney father participate in a local theater group. Three years later, Braff could be found cultivating his own show-business skills at Stagedoor Manor, a renowned children's acting camp. After attracting the attention of a well-connected talent scout, Braff made his would-have-been television debut opposite Gwyneth Paltrow in an unsold pilot produced by Bruce Paltrow. His contribution to CBS's after-school special My Summer as a Girl in 1994 made it to the television screen, but, by that time, he had a significantly more notable role under his belt: the teenaged son of two neurotic New Yorkers (Woody Allen and Diane Keaton) in Manhattan Murder Mystery (1993). Though moderately successful in his childhood and late teens, Braff opted to attend college at Northwestern University rather than making an immediate transition to a full-time career of pursuing roles in the wilds of Los Angeles. While at Northwestern, Braff wrote and directed several short films, among them Lionel on a Sunday, which fared successfully in the 1998 festival season. The young actor went on to co-star in Getting to Know You, an adaptation of various short stories penned by author Joyce Carol Oates, which won praise at the 1999 Sundance Film Festival. After a role as a gay party-boy drug addict in The Broken Hearts Club (2000), which won a GLAAD Media Award for Outstanding Film, Braff auditioned for Scrubs; despite his prior experience, the sitcom undoubtedly became his breakout role. Indeed, the Scrubs success helped Braff write, direct, and star in Garden State (2003) opposite Natalie Portman and Ian Holm. The "little Sundance film that could" of its particular year, Garden State became a major indie hit, as its look and sound resonated with the creeping-toward-maturity Gen-Y demographic to whom Braff was obviously appealing. His next role as the lead character in Disney's animated Chicken Little appealed to a younger crowd, but still banked some serious cash at the box office. Braff next appeared in the flesh in 2006's Tony Goldwyn romantic comedy The Last Kiss. The film, scripted by Crash's Paul Haggis, co-starred Casey Affleck, Tom Wilkinson, and Blythe Danner, and mined much of the same simultaneously sad and funny emotional ground explored in Garden State. It died a quick death at theaters as fans heeded the advice of critics who deemed it a more morose gloss on well-trod twentysomething angst. The actor's next film was the lighter romantic-triangle comedy The Ex.Scrubs finally ended its run in 2011, and Braff made another big screen appearance, this time in the drama The High Cost of Living. He had a supporting role in 2013's Oz the Great and Powerful before returning to the indie scene in 2014 with the Kickstarter-funded Wish I Was Here, which he directed, co-wrote (with his brother Adam) and starred in.

Trivia: Ottawa-born Sarah Chalke first gained notoriety in 1993 when, at the beginning of the show's sixth season, she was cast on ABC's hit sitcom Roseanne as oldest daughter Becky, a role that had previously been filled by Alicia Goranson, who exited the show for college. Chalke continued to play Becky for two seasons until Goranson returned, but the two actresses took turns playing the character throughout the season. Goranson left again before the show's ninth and final season, and Chalke resumed the role full-time.Following the end of Roseanne, Chalke took on a role in the Canadian series Nothing Too Good for a Cowboy. While that show only lasted nine episodes, it would only be a couple more years before the actress found herself on another hit series. In 2001, she was cast as Elliot Reid, the female lead opposite Zach Braff on the cult hit NBC medical comedy Scrubs. The massively successful show would run until 2010, earning Chalke legions of fans.In addition to her series television work, Chalke has acted in a number of made-for-TV movies and small independent films over the years. In 2007 she had her first role in a high-profile Hollywood movie with a supporting turn alongside Jon Heder and Diane Keaton in the comedy Mama's Boy. She would also find continued success on the small screen, with starring roles on shows like Mad Love, a recurring gig on Cougar Town and guest spots on shows like Grey's Anatomy and Angie Tribeca.

Trivia: Comedic actor Donald Faison began his acting career with bit parts in gritty urban dramas like Juice and Sugar Hill before breaking through with a supporting role in the hit 1995 comedy Clueless. A year later, he was one of the few cast members to make the leap to the film's TV spin-off and stuck with the show throughout its three-year run. After Clueless bowed, Faison wasted little time before joining the cast of the popular drama Felicity. But it was in 2001 that he would land his most noteworthy role, that of surgeon Dr. Christopher Turk on the hit NBC medical-sitcom Scrubs. When Scrubs ended in 2010, Faison immediately jumped to another show, the TV Land sitcom The Exes.

Trivia: John McGinley, often credited as John C. McGinley, has become one of the most prolific character actors in Hollywood since he first got noticed in Oliver Stone's Platoon (1986). The intense, unblinking actor specializes in sarcasm, cynicism, and a used car dealer's unctuous insincerity, meaning he can play either wacky or sinister in both comedies and dramas. Although he has appeared in six Stone films, his breakout performance came in a very different format, as the acerbic and piercingly straightforward Dr. Perry Cox on the hit NBC sitcom Scrubs (2001).McGinley was born on August 3, 1959, in New York City. Growing up in Millburn, NJ, he was more involved in sports than theater. He began studying acting at Syracuse University, continuing at N.Y.U.'s Tisch School of the Arts. McGinley then toiled both on and off-Broadway, as well as two years on the soap opera Another World, scoring his first film role in the Alan Alda-directed Sweet Liberty (1986). It was while he was serving as John Turturro's understudy on the play Danny and the Deep Blue Sea that a casting scout in Stone's employ spotted him and got him an audition for Platoon. McGinley was cast as the sycophantic Sgt. Red O'Neill in the eventual Oscar winner.McGinley followed up Platoon with another one-two punch of Stone movies, Wall Street (1987) and Talk Radio (1988). In interviews, McGinley has described theirs as a "strong working relationship," not a friendship per se with the demanding director. He appeared in a handful of other films before his fourth Stone collaboration, Born on the Fourth of July (1989), which was quickly followed by his first screenwriting effort. McGinley co-scripted and co-starred in the 1990 film Suffering Bastards, alongside Talk Radio's Eric Bogosian.The 1990s were a period of intense work for the actor, who appeared in an average of three movies a year, sometimes as many as seven -- a necessary but no less tricky feat for a character actor earning modest paychecks. The most heralded of these were David Fincher's Seven and Stone's Nixon (both 1995); the most forgettable were Highlander II: The Quickening (1991) and the Steven Seagal starrer On Deadly Ground (1994). For most moviegoers, he remained under the radar.Two showy roles in 1999 ably demonstrated McGinley's facility for comedy. As a callous efficiency expert brought aboard to reorganize (i.e., downsize) the tech firm at the heart of Office Space, McGinley grinned and joked his way through a round of heartless layoffs. A similar oiliness informed his loud, obnoxious, kiss-ass portrayal of a Jim Rome-type sports interviewer in Stone's Any Given Sunday. It was soon after, in 2001, that McGinley was brought aboard for the role destined to identify him beyond any single film. As the default mentor on Scrubs, McGinley alternated hard-knocks frankness, biting wit, and a genuine desire to be left alone, in turn creating a hilarious persona and sealing his fate as an unwitting cult figure to the young surgeons. The sitcom work schedule has given him the necessary stability to spend time with his young son, Max, who has Down's syndrome.

Trivia: After nearly a decade of appearing in guest roles on everything from The Cosby Mysteries to The Sopranos, and after a recurring role on the prison drama Oz, Bronx-born Judy Reyes gained prominence in 2001 when she was cast as the feisty Nurse Carla Espinosa on NBC's medical comedy Scrubs.

Trivia: After building a career as a character actor playing dozens of military men and cops, Ken Jenkins founds steady work and notoriety in 2001 when he was cast as Chief of Medicine Dr. Bob Kelso on NBC's Scrubs. Born in New Boston, OH, Jenkins began acting on the stage in the 1960s and continued to be a presence in the theater world throughout the '70s and into the '80s before transitioning to a screen career. His film roles included such varying and prominent features as Matewan and The Abyss, and his TV work included work on everything from Newhart to Star Trek: The Next Generation. In 1991, Jenkins got his first taste of regular series work when he was cast on the acclaimed family drama Homefront, which lasted two seasons. More supporting work followed before the creators of Scrubs came knocking and offered the role for which he would come to be best known. He would appear on the show until 2010, after which he took on a recurring role on the series Cougar Town.

Trivia: Comedic actor Neil Flynn cut his teeth with the renowned improv companies Second City and ImprovOlympic, the latter of which saw him study under the late improv guru Del Close. Despite his comedy-oriented aspirations, though, Flynn spent much of his early career taking bit parts in films like The Fugitive and Magnolia and on TV shows such as Doogie Howser, M.D. and Chicago Hope, often playing a cop. But in 2001, things took a decidedly positive turn when he was cast as the nameless Janitor on NBC's Scrubs, a role that was intended only for the pilot but was expanded to a regular series character in light of Flynn's performance. In addition to his live-action work, Flynn has also done a considerable amount of voice work on such animated projects as Clone High, Kim Possible, and Cloudy with a Chance of Meatballs. Flynn left Scrubs after season 8 and took a starring role in the ABC comedy The Middle, playing patriarch Mike Heck

Trivia: Appeared in movie Naked Gun 33 1/3: The Final Insult when he was 12 years old. TV credits include The Amanda Show and Scrubs. In 2001, became the youngest cast member of MADtv at age 19. Became a member of the main company of Los Angeles improvisational group the Groundlings in April 2010. Started on Saturday Night Live in September 2010.

Trivia: After graduating high school, worked as a nurse; has since played a nurse in several TV shows and films. Started her acting career with stage shows, appearing in the play First Breeze of Summer in 1994. Her character on Scrubs was written out of the show when they expected it to be canceled; when it was instead renewed, she was written back on with a new character. Appeared in over 260 episodes of Days of Our Lives between 2008 and 2015. Marched in the 83rd Annual Hollywood Christmas Parade, which honored the cast of Days of Our Lives.