Barbarian attacks along Rome's northern borders intensify, beginning the period of Rome's decline. One of the most famous doctor/scientists of the ancient world, Galen of Pergamon makes a name for himself as a physician for gladiators in the arena. But just as Rome's Empire reaches the height of its power and influence under Emperor Marcus Aurelius, a devastating plague sweeps through the city and Galen catches the attention of Emperor Marcus Aurelius.