Trivia: Many know actress Kellie Shanygne Williams for her role as Laura Winslow on the sitcom Family Matters. Williams played the role for the series' entire run, from 1989 to 1998. She then made a number of guest appearances on various TV shows like What About Joan and The Parkers, and in 2009, she became the host of the reality series Clean House.

Trivia: Comedienne Ann Ryerson honed her skills with the best in the business, performing in the legendary Second City improve troupe with Harold Ramis in the 1970s. She would later appear in the classic 1980 comedy Caddyshack and built up her résumé throughout the '80s with a string of guest appearances on TV shows like Benson and Murphy Brown. Ryerson would continue the streak in the '90s, as well, playing a wide variety of characters on everything from Family Matters to Dream On. She also appeared in a number of movies, including 2002's Minority Report and 2005's Constantine. Ryerson also took on a memorable recurring role on the popular comedy series Curb Your Enthusiasm.

Trivia: African-American actor Reginald VelJohnson is the ideal choice for "urban everyman" roles: his sour-apple facial expression, bald pate, and chubby frame are perfectly suited for the many policemen and blue-collar workers he has played over the years. Beginning in small parts in films like Ghostbusters (1984), VelJohnson gained a following with supporting roles in Crocodile Dundee (1986) and Die Hard (1988). A guest spot as an undercover cop on a 1989 episode of TV's Perfect Strangers led to VelJohnson's longest professional engagement to date. In the company of former Perfect Strangers regular Jo-Marie Payton-France, Reginald VelJohnson, since the fall of 1989, starred as Chicago cop Carl Winslow on the weekly comedy series Family Matters.

Trivia: Jaleel White ascended to cult stardom during his early teenage years with a now-iconic portrayal of über-nerd Steve Urkel on the Friday-night ABC sitcom Family Matters (1989-1998). A veteran of television commercials and guest spots on various prime-time series from early childhood, White appeared as a regular on the short-lived CBS sitcom Charlie & Co. (1985-1986), starring Flip Wilson and Gladys Knight. The Urkel role, however, brought about his greatest popularity, and he landed it not long after the series first bowed in late September 1989 (appearing as early as the 12th episode). Though originally intended as a one-episode guest star, White generated massive popularity among audience members -- encouraging producers Tom Miller and Robert Boyett to rethink their strategy for the show. Urkel quickly became not only a fixture, but the program's lucky charm -- the wild card that turned it into a number one hit, much as the same producers had done with The Fonz, years prior, on Happy Days. Over the course of the program's run, White ascended to prominent billing (also mirroring the Fonzie situation). Unfortunately, as time passed, the Urkel characterization became increasingly difficult to sustain, thanks in no small part to White's accelerating age and height -- which dealt the series writers an incredibly difficult hand and forced them to figure out bizarre ways to work around this handicap (strategies included giving Urkel a "cool" alter-ego, Stefan, and affording that persona a great deal of screen time).The program wrapped in 1998, but in the meantime, White graduated from UCLA Film School, then moved into his heart's true calling -- that of screenwriting. He authored occasional teleplays for such venues as The Disney Channel and PBS, moved into big-screen work (with projects including a feature rewrite for director Joel Zwick), and continued to act on the side. Roles included lead billing in Damon Daniels' independent feature Who Made the Potatoe Salad? (2005) and a supporting contribution to the inspirational volleyball drama Green Flash (2008). He was in the low-budget Mega Shark vs. Crocosaurus, and in 2011 he played a teacher in Judy Moody and the NOT Bummer Summer. In 2012 the artist formerly known as Urkel competed on the 14th season of the popular ABC reality series Dancing With the Stars.

Trivia: An actor with a penchant for getting hired in as a series regular on one-hour TV shows, Jensen Ackles left his native Texas to pursue an acting career after graduating from high school. His big break came in 1997, when he was cast in the role of Eric Brady on the soap opera Days of Our Lives. He made regular appearances on the show over the next three years, winning a Best Male Newcomer award from Soap Opera Digest and getting nominated for a Daytime Emmy no less than three times. Ackles left Days of Our Lives in 2000 and shortly thereafter appeared in an episode of the James Cameron adventure series Dark Angel, playing a psychotic, murderous X5 (a genetically engineered superhuman) named Ben. Ackles was brought back as a regular the next season, playing the less sinister twin/clone of Ben, Alec, who reluctantly aided Jessica Alba's Max from time to time despite his cocky, selfish nature. In 2002, Ackles moved on to join the cast of the WB series Dawson's Creek for its sixth and final season, and when that show wrapped he took a role on another WB series, Smallville. He'd auditioned for the leading role of Clark Kent when the series first went into production in 2001, and lost the part to Tom Welling, but this time Ackles was cast as Jason Teague, love interest of Lana Lang. Then in 2005, Ackles nabbed a part on yet another TV series, and this time he won the lead. In the role of Dean Winchester on Supernatural, Ackles played a young man who investigates paranormal activity with his brother. The show was a hit, picking up a few Emmy and Saturn Award nominations, and as the show rocketed through season after season, Ackles' star continued to rise, also providing him the chance to direct episodes as well.

Trivia: Texas native Jared Padalecki was only 12 years old when he started studying acting. He took to the stage all throughout high school, competing on his school's speech team and appearing in school plays. In 1999, the 17-year-old won Fox's "Claim to Fame" contest and had the chance to appear at the Teen Choice Awards. The opportunity led to the young actor signing up with an agent and beginning his professional career. He began scoring appearances on shows and in TV movies, playing the victim of a car accident on an episode of ER and a wealthy suitor in Ring of Endless Light. Then in 2001, Padalecki was cast as Dean Forester, love interest of Rory Gilmore on the hit series Gilmore Girls. He stayed with the show until 2005, when he joined up with the sci-fi thriller series Supernatural. Padalecki also ventured onto the big screen, appearing in films like House of Wax and The Christmas Cottage.