Philadelphia Eagles (10-5) at Buffalo Bills (11-4). From Highmark Stadium. NFL rushing leader James Cook (1532 yards) and 2024 rushing king Saquon Barkley share the ball-carrying load with dual-threat QBs Josh Allen and Jalen Hurts in a clash of playoff qualifiers riding roller-coaster seasons since starting 4-0. Other Pro Bowlers include Bills tackle Dion Dawkins and Philly CB Cooper DeJean.