New England Patriots (2-2) at Buffalo Bills (4-0). From Highmark Stadium. The Bills' ground game led by James Cook (three straight 100-yd. games) and QB Josh Allen look to spoil the prime-time debut for the Pats under Mike Vrabel, who are chasing their first win in Orchard Park since 2021--when they won with just three pass attempts. New England's TreVeyon Henderson is a rookie playmaker to watch.