Trivia: For better or worse, leading actor Kelsey Grammer's name will probably forever be associated with the pompous, garrulous, and self-absorbed but lovable psychiatrist Frasier Crane, a character Grammer has played on television since he first appeared on the NBC sitcom Cheers, in 1984, as a love interest for Shelley Long. Though Frasier was not intended to become a series regular, Grammer's performance of the blowhard neurotic charmed audiences and he remained with Cheers through its 1993 demise. At the beginning of the 1993-1994 television season, Grammer's character was resurrected in his own show and moved from Boston to Seattle, where he became a radio psychologist and faced a whole slew of folks just waiting to poke metaphorical pins in his hot air balloon. Thanks to excellent performances and top-notch writing, Frasier became as big a hit as its predecessor. Grammer won three Emmy awards and was nominated for seven more (twice for Cheers, once for his guest appearance on a 1992 episode of Wings, four times for Frasier) for playing the character. Born on St. Thomas, one of the U.S. Virgin Islands, Grammer knew extreme tragedy in youth. Following the shooting death of his father when he was a boy, he was raised in New Jersey and then Florida, by his mother and grandfather. His grandfather died before Grammer became a teen. When he was 20, his sister was abducted and violently murdered. Five years later, he lost two half brothers in a diving accident. As a young man, Grammer found comfort in Shakespeare; with his acting debut in a high school production of The Little Foxes came an interest in pursuing drama as a career. He enrolled in Juilliard, but dropped out after two years to work at San Diego's Old Globe Theater, where he gained three years' invaluable experience performing in Shakespearean and classical dramas; afterward, Grammer performed in productions across the country. He eventually made it to Broadway, where he appeared in various productions, including Othello. Prior to playing Frasier, Grammer appeared occasionally on television and had regular roles in three soap operas, including One Life to Live. He continues to occasionally guest star on other series. Fans of the animated satire The Simpsons will recognize his periodic voice characterization as the venomous Sideshow Bob. Miniseries and telemovies in which he has appeared include London Suite and Beyond Suspicion. Grammer made his feature film debut with a small role in Top of the Hill (1989) and had his first starring role in the much-panned comedy Down Periscope (1996). In addition to his Emmy kudos, Grammer has received an American Comedy Award, two Golden Globes, and a People's Choice Award. In 1995, he published his autobiography So Far.Grammer would spend the following years taking on TV roles on shows like Back to You and Boss, but would find even more success as a producer, helping bring shows like The Game, Girlfriends, Hank, Medium, and World Cup Comedy to fruition. In 2014, he returned to acting in a big way, making a cameo appearance in X-Men: Days of Future Past, reprising his role as Beast, playing the bad guy in Transformers: Age of Extinction, and returning to television in the FX series Partners.

Trivia: Although he is best known for his role as anal-retentive psychiatrist extraordinaire Niles Crane on the celebrated sitcom Frasier, David Hyde Pierce has also done considerable work on the stage and screen. Fair, birdlike, and bearing an uncanny resemblance to Frasier co-star Kelsey Grammer, Pierce is one of the entertainment business' finest purveyors of a certain kind of blue-blooded neuroticism, and, in the eyes of some viewers, has even gone so far as to make insecurity perversely sexy.Born in Saratoga Springs, New York, on April 3, 1959, Pierce was raised in what he has described as a "very run-of-the-mill, middle-class" household. When he was eight, he began taking piano lessons, and he decided to pursue a career as a concert pianist. He continued to train until he got to Yale University, where he realized that he was better suited to the acting profession. Following graduation, Pierce moved to New York and did a brief stint as a tie salesman at Bloomingdale's before being cast in a Broadway play. Although the production was a flop, Pierce continued to work on the stage in New York and Chicago for several years and was eventually cast as a suicidal congressman on the short-lived sitcom The Powers That Be in 1992. His work on the show, coupled with his resemblance to Kelsey Grammer, led to his casting on Frasier the following year.Frasier proved to be the turning point in Pierce's career. His portrayal of Niles, aside from winning him a slew of awards, including an Emmy, also provided a number of opportunities for the actor on the big screen. Pierce, who had been acting sporadically in films since the early '80s, could be seen in supporting roles in such '90s films as Sleepless in Seattle (1993), Nixon (1995), in which he played John Dean, and the animated A Bug's Life (1998), for which he provided the voice of a stick insect.As the first decade of the 21st century opened, Pierce began appearing in more and more feature films, selecting an eclectic array of roles that utitlized his strengths without resorting to rehashing the Niles Crane character. Diverse in their genre and theme, the projects also ranged in their levels of success and acclaim. The 2000 comedy Isn't She Great was an abysmal failure, while the indie films Wet Hot American Summer and Full Frontal both left audiences and critics fiercely split. Pierce also continued to flex his voice skills in the animated features Osmosis Jones and Treasure Planet.One of Pierce's best-received roles came in 2003, when he costarred in the tongue-in-cheek comedy Down With Love. While not much of a box-office hit, the film managed to charm many critics with its wall-to-wall homages to 1960s sex-comedies. A year later, Pierce again showed up sans-body, providing the voice of Abe Sapien in the comic-book adaptation Hellboy. He reunited with Hellboy creator Mike Mignola's animated comic adaptation The Amazing Screw-On Head to voice the role of the dreaded Emperor Zombie in 2006, and joined the cast of The Perfect Host in 2010 for a leading role as Warwick Wilson, whose genteel façade hides a deep rage and mental instability.

Trivia: A distinctive-looking, grey-haired British character actor, John Mahoney worked onstage in his teens, and moved to the U.S. at 19. In his mid-30s, while employed as an editor in Chicago, he decided to renew his interest in acting, and he enrolled in classes at a local theater co-founded by playwright David Mamet; he landed a role in a Mamet play and left his job for the part. At the urging of actor John Malkovich, he went on to join Chicago's celebrated Steppenwolf Theater; eventually he appeared in more than 30 plays. For his work in the Broadway play House of Blue Leaves he won a Tony and a Clarence Derwent Award. For his work in the lead role of Orphans (on Broadway and in Chicago) he won a Theater World Award. He still lives in Chicago, and maintains his connection with Steppenwolf. Mahoney debuted onscreen in Mission HIll (1982), but his screen breakthrough came in his fifth film, Barry Levinson's popular comedy Tin Men (1987); afterwards he went on to better parts in more noteworthy movies, and has avoided typecasting in a busy screen career. Mahoney's TV credits include Favorite Son and House of Blue Leaves, in which he reprised his stage role; he has since achieved wide popularity as Martin Crane, Frasier Crane's crochety father, on the NBC sitcom Frasier.

Trivia: Began studying ballet at a very early age, but hurt her ankle when she was 18 and was forced to give it up. Appeared in David Lee Roth's video for "California Girls." Lived for a time with her best friend Faith Ford, whom she met in acting class. Cofounded the production company Bristol Cities with Frasier costar Peri Gilpin in 1998. Since her first pregnancy wasn't written into Frasier, her character, Daphne, was sent off to a fat camp and was said to have lost 9 pounds, 12 ounces---the weight of Jane's daughter when she was born. Made her Broadway debut in Cabaret as Sally Bowles in 2002. Reunited with Fraiser alum Wendy Malick to costar in the TV Land sitcom Hot in Cleveland.

Trivia: With a father who was a famous local radio and television celebrity, a model mother who appeared in television, and a working relationship with Wings producer Roz Doyle in her past, it may all seem like an obscure cosmic joke that pretty Peri Gilpin would rise to fame as radio producer Roz Doyle on the smash television sitcom Frasier, though the longtime actress would likely credit her success to hard work rather than astrological coincidence.Born in Waco, TX, and raised in Dallas, Gilpin began acting on stage with the Dallas Theater Company at the age of eight, a fact that helped her shake stage fright and gain the confidence that would accompany her through numerous future auditions. A Skyline High School graduate, Gilpin later studied acting at both the University of Texas at Austin and London's British-American Academy. Upon returning to the U.S., Gilpin worked as a makeup artist in the Dallas area before taking an apprenticeship with the Williamstown Theater Festival. A chance meeting with actress Blythe Danner resulted in Gilpin gaining some support within the industry, and it wasn't long before Gilpin's dreams were coming true with roles on television's Flesh 'n' Blood and 21 Jump Street. A role on Cheers followed shortly after, and when a spin-off series entitled Frasier became an unexpected hit, Gilpin found the role that would bring her into households across the country on a weekly basis. Appearing frequently on such made-for-television films as The Secret She Carried (1996) and Laughter on the 23rd Floor (2000) while simultaneously essaying her role on Frasier, Gilpin (who was named after the animated Disney character Peri the squirrel) has also loaned her voice to such animated projects as television's Hercules and the computer-animated feature Final Fantasy: The Spirits Within (2001). Throughout the 2000's and 2010's, Gilpin remained active, starring most notably on the dance series Make It or Break It.

Trivia: Tall, thin, and blonde, Oscar-nominated actress Lindsay Crouse has been appearing onscreen since the mid-'70s -- though contemporary, television-savvy fans may be more familiar with her thanks to memorable small-screen roles on Buffy the Vampire Slayer, Providence, and Hack. Crouse is a New York City native and the daughter of Life With Father author Russel Crouse; her literary father named her after his longtime writing partner Howard Lindsay. An education at Radcliffe first led Crouse to a career as a dancer, though it wasn't long before she began leaning toward acting; she made her screen debut in 1976's All the President's Men. Roles in Slap Shot (1977) and The Verdict (1982) found Crouse managing to hold her own opposite screen heavy Paul Newman, and after remaining under the direction of Sidney Lumet for Daniel (1983), Crouse earned an Oscar nod for her performance opposite Sally Field in the 1984 drama Places in the Heart. With the exception of a season of Hill Street Blues, Crouse would stick mainly to feature films for the remainder of the 1980s. Her leading role as a conflicted psychiatrist in 1987's House of Games (under the direction of then-husband David Mamet) seemed to capitalize on her status as one of John Willis' Screen World's "Most Promising New Actors of 1984." If the 1990s found Crouse edging almost exclusively into small-screen work, the occasional feature, such as The Juror (1996) and Prefontaine (1997), proved that she had lost none of her enduring big-screen appeal. Indeed, Crouse was equally effective in both film and television; small-screen roles in Norma Jean and Marilyn and If These Walls Could Talk (both 1996) proved just as compelling as her turn in Michael Mann's acclaimed 1999 drama The Insider. In 2000, Crouse took on the role of Caroline Ingalls in the made-for-TV family film Beyond the Prairie: The True Story of Laura Ingalls Wilder. Before returning to the character in the 2002 sequel, she played supporting roles in Imposter and Cherish (both 2002).

Trivia: While most rising stars would be reluctant to tarnish their all-American image by appearing in films that demand they morph into another gender or in television roles that call for them to be as prickly as possible, handsome theater veteran Taylor Handley is always willing to throw the viewing audience the kind of curveballs that set him well apart from the pack. Born and raised in Santa Barbara, CA, Handley took to acting at the tender age of eight and cut his teeth in summer stock. While few of the aspiring actor's early television appearances -- including bit roles in Frasier, Touched By an Angel, and CSI -- would call for anything out of the ordinary, more substantial roles in Dawson's Creek and The O.C. began to reveal an actor of unusual complexity and ambition. It was his role as bad-boy Oliver Trask on The O.C., in particular, that first brought Handley to the attention of many television viewers, yet even with that edgy performance on his resumé, few could have foreseen something as strange as his role in the decidedly off-kilter romantic comedy Zerophilia a couple years later. Cast as an insecure teen boy who realizes he is gradually morphing into a female in writer/director Martin Curland's gender-bending film, Handley went places that few rising stars would be bold enough to venture. Handley next appeared in the period drama September Dawn, which detailed the historic confrontation between a traveling band of peaceful settlers and a renegade Mormon group. He could also be seen in the rip-roaring horror sequel Texas Chainsaw Massacre: The Beginning, which pitted him against one of the most notorious madmen in screen history. Back on the small screen, following an appearance on CSI: Miami, Handley scored the lead role of Johnny Miller on the weekly guilty pleasure Hidden Palms. Scripted by Dawson's Creek mastermind Kevin Williamson, Hidden Palms told the tale of a troubled teen (Handley) doing his best to recover from his father's recent suicide and a stint in rehab by connecting with the angst-ridden kids who inhabit his new Palm Springs neighborhood.

Trivia: With his doe eyes and April-fresh skin, Freddie Prinze Jr. seemed a natural leader of the late-'90s Hollywood teen invasion. Noted as much for his looks as for his acting, Prinze has proven to have a natural appeal that has endured him to legions of fans.The beginning of Prinze's life was a turbulent one, as his father, the actor Freddie Prinze (best known for his starring role on NBC's Chico and the Man) committed suicide when the younger Prinze was only ten months old. Born in Los Angeles on March 8, 1976, Prinze moved with his mother to Albuquerque, NM, shortly after his father's death. Growing up in New Mexico, Prinze was a poor student who decided to follow in his father's celluloid footsteps. After his high-school graduation in 1994, Prinze took off for Los Angeles with little money and few prospects. However, he soon found work in Hollywood, first appearing in various television shows, including an episode of Family Matters and a few afterschool specials.The actor first broke into film as Claire Danes' boyfriend in To Gillian on Her 37th Birthday (1996). The part was a small one, but helped Prinze to secure his next and more sizeable role in The House of Yes (1997), a wicked little black comedy that starred Parker Posey as Prinze's deliciously unstable sister. The film's release was mainly limited to art houses, unlike Prinze's next film, I Know What You Did Last Summer (1997). The film was a huge commercial, if not critical, success that propelled Prinze into, if not the limelight, then the hearts of many girls and more than a few boys everywhere. Following this triumph, Prinze went on to do a couple of forgettable films before the 1998 sequel I Still Know What You Did Last Summer. The combined impact of that film and the success of Prinze's next major project, She's All That, gave the actor even greater fame and caused least one writer to dub him the next Leonardo Di Caprio. Unfortunately, Prinze's following endeavor, Wing Commander (1999), proved to be an unmitigated disappointment, serving to illustrate the extreme fluctuations of success in Hollywood. Prinze's growing popularity, however, seemed to survive relatively unscathed, judging by the slew of websites erected in his name.If there was any question that the actor's popularity was waning in the wake of Wing Commander's lackluster performance, that doubt would soon be confirmed with hard numbers, as a triple threat of romantic comedies unceremoniously removed the teen-crowd superstar crown from Prinze's head. The cookie-cutter offerings Down to You and Boys and Girls (the latter of which reteamed him with She's All That director Robert Iscove) attempted to posit Prinze as a collegiate heartthrob, but both films' mix of moony romance with gross-out gags did little to attract moviegoers of any age. Anticipation for his next starring role, alongside Jessica Biel and Matthew Lillard in 2001's Summer Catch, was understandably low; the film was even saddled with a late-August release, traditionally reserved by studios as a "dumping ground" for unpromising product. As it turned out, Summer Catch's mixed reviews proved more forgiving than its paltry $19 million take.Prinze's next project brought him out of the romantic comedy trend and into the doghouse, or at least the Mystery Machine. Re-teaming with his usual foil Lillard and starring -- yet again -- opposite his longtime love interest Sarah Michelle Gellar, Prinze took on the role of Fred in the live-action adaptation of Scooby-Doo in 2002. Though almost universally panned by critics, the film reversed Prinze's dwindling status as a box-office draw by appealing to a demographic he'd yet to conquer: preteens. Not one to look a gift franchise in the mouth, Prinze signed on for another installment, Scooby-Doo 2: Monsters Unleashed, and took nearly two years off between the blockbusters as he tied the knot with Gellar.