Trivia: For better or worse, leading actor Kelsey Grammer's name will probably forever be associated with the pompous, garrulous, and self-absorbed but lovable psychiatrist Frasier Crane, a character Grammer has played on television since he first appeared on the NBC sitcom Cheers, in 1984, as a love interest for Shelley Long. Though Frasier was not intended to become a series regular, Grammer's performance of the blowhard neurotic charmed audiences and he remained with Cheers through its 1993 demise. At the beginning of the 1993-1994 television season, Grammer's character was resurrected in his own show and moved from Boston to Seattle, where he became a radio psychologist and faced a whole slew of folks just waiting to poke metaphorical pins in his hot air balloon. Thanks to excellent performances and top-notch writing, Frasier became as big a hit as its predecessor. Grammer won three Emmy awards and was nominated for seven more (twice for Cheers, once for his guest appearance on a 1992 episode of Wings, four times for Frasier) for playing the character. Born on St. Thomas, one of the U.S. Virgin Islands, Grammer knew extreme tragedy in youth. Following the shooting death of his father when he was a boy, he was raised in New Jersey and then Florida, by his mother and grandfather. His grandfather died before Grammer became a teen. When he was 20, his sister was abducted and violently murdered. Five years later, he lost two half brothers in a diving accident. As a young man, Grammer found comfort in Shakespeare; with his acting debut in a high school production of The Little Foxes came an interest in pursuing drama as a career. He enrolled in Juilliard, but dropped out after two years to work at San Diego's Old Globe Theater, where he gained three years' invaluable experience performing in Shakespearean and classical dramas; afterward, Grammer performed in productions across the country. He eventually made it to Broadway, where he appeared in various productions, including Othello. Prior to playing Frasier, Grammer appeared occasionally on television and had regular roles in three soap operas, including One Life to Live. He continues to occasionally guest star on other series. Fans of the animated satire The Simpsons will recognize his periodic voice characterization as the venomous Sideshow Bob. Miniseries and telemovies in which he has appeared include London Suite and Beyond Suspicion. Grammer made his feature film debut with a small role in Top of the Hill (1989) and had his first starring role in the much-panned comedy Down Periscope (1996). In addition to his Emmy kudos, Grammer has received an American Comedy Award, two Golden Globes, and a People's Choice Award. In 1995, he published his autobiography So Far.Grammer would spend the following years taking on TV roles on shows like Back to You and Boss, but would find even more success as a producer, helping bring shows like The Game, Girlfriends, Hank, Medium, and World Cup Comedy to fruition. In 2014, he returned to acting in a big way, making a cameo appearance in X-Men: Days of Future Past, reprising his role as Beast, playing the bad guy in Transformers: Age of Extinction, and returning to television in the FX series Partners.

Trivia: Although he is best known for his role as anal-retentive psychiatrist extraordinaire Niles Crane on the celebrated sitcom Frasier, David Hyde Pierce has also done considerable work on the stage and screen. Fair, birdlike, and bearing an uncanny resemblance to Frasier co-star Kelsey Grammer, Pierce is one of the entertainment business' finest purveyors of a certain kind of blue-blooded neuroticism, and, in the eyes of some viewers, has even gone so far as to make insecurity perversely sexy.Born in Saratoga Springs, New York, on April 3, 1959, Pierce was raised in what he has described as a "very run-of-the-mill, middle-class" household. When he was eight, he began taking piano lessons, and he decided to pursue a career as a concert pianist. He continued to train until he got to Yale University, where he realized that he was better suited to the acting profession. Following graduation, Pierce moved to New York and did a brief stint as a tie salesman at Bloomingdale's before being cast in a Broadway play. Although the production was a flop, Pierce continued to work on the stage in New York and Chicago for several years and was eventually cast as a suicidal congressman on the short-lived sitcom The Powers That Be in 1992. His work on the show, coupled with his resemblance to Kelsey Grammer, led to his casting on Frasier the following year.Frasier proved to be the turning point in Pierce's career. His portrayal of Niles, aside from winning him a slew of awards, including an Emmy, also provided a number of opportunities for the actor on the big screen. Pierce, who had been acting sporadically in films since the early '80s, could be seen in supporting roles in such '90s films as Sleepless in Seattle (1993), Nixon (1995), in which he played John Dean, and the animated A Bug's Life (1998), for which he provided the voice of a stick insect.As the first decade of the 21st century opened, Pierce began appearing in more and more feature films, selecting an eclectic array of roles that utitlized his strengths without resorting to rehashing the Niles Crane character. Diverse in their genre and theme, the projects also ranged in their levels of success and acclaim. The 2000 comedy Isn't She Great was an abysmal failure, while the indie films Wet Hot American Summer and Full Frontal both left audiences and critics fiercely split. Pierce also continued to flex his voice skills in the animated features Osmosis Jones and Treasure Planet.One of Pierce's best-received roles came in 2003, when he costarred in the tongue-in-cheek comedy Down With Love. While not much of a box-office hit, the film managed to charm many critics with its wall-to-wall homages to 1960s sex-comedies. A year later, Pierce again showed up sans-body, providing the voice of Abe Sapien in the comic-book adaptation Hellboy. He reunited with Hellboy creator Mike Mignola's animated comic adaptation The Amazing Screw-On Head to voice the role of the dreaded Emperor Zombie in 2006, and joined the cast of The Perfect Host in 2010 for a leading role as Warwick Wilson, whose genteel façade hides a deep rage and mental instability.

Trivia: A distinctive-looking, grey-haired British character actor, John Mahoney worked onstage in his teens, and moved to the U.S. at 19. In his mid-30s, while employed as an editor in Chicago, he decided to renew his interest in acting, and he enrolled in classes at a local theater co-founded by playwright David Mamet; he landed a role in a Mamet play and left his job for the part. At the urging of actor John Malkovich, he went on to join Chicago's celebrated Steppenwolf Theater; eventually he appeared in more than 30 plays. For his work in the Broadway play House of Blue Leaves he won a Tony and a Clarence Derwent Award. For his work in the lead role of Orphans (on Broadway and in Chicago) he won a Theater World Award. He still lives in Chicago, and maintains his connection with Steppenwolf. Mahoney debuted onscreen in Mission HIll (1982), but his screen breakthrough came in his fifth film, Barry Levinson's popular comedy Tin Men (1987); afterwards he went on to better parts in more noteworthy movies, and has avoided typecasting in a busy screen career. Mahoney's TV credits include Favorite Son and House of Blue Leaves, in which he reprised his stage role; he has since achieved wide popularity as Martin Crane, Frasier Crane's crochety father, on the NBC sitcom Frasier.

Trivia: Began studying ballet at a very early age, but hurt her ankle when she was 18 and was forced to give it up. Appeared in David Lee Roth's video for "California Girls." Lived for a time with her best friend Faith Ford, whom she met in acting class. Cofounded the production company Bristol Cities with Frasier costar Peri Gilpin in 1998. Since her first pregnancy wasn't written into Frasier, her character, Daphne, was sent off to a fat camp and was said to have lost 9 pounds, 12 ounces---the weight of Jane's daughter when she was born. Made her Broadway debut in Cabaret as Sally Bowles in 2002. Reunited with Fraiser alum Wendy Malick to costar in the TV Land sitcom Hot in Cleveland.

Trivia: With a father who was a famous local radio and television celebrity, a model mother who appeared in television, and a working relationship with Wings producer Roz Doyle in her past, it may all seem like an obscure cosmic joke that pretty Peri Gilpin would rise to fame as radio producer Roz Doyle on the smash television sitcom Frasier, though the longtime actress would likely credit her success to hard work rather than astrological coincidence.Born in Waco, TX, and raised in Dallas, Gilpin began acting on stage with the Dallas Theater Company at the age of eight, a fact that helped her shake stage fright and gain the confidence that would accompany her through numerous future auditions. A Skyline High School graduate, Gilpin later studied acting at both the University of Texas at Austin and London's British-American Academy. Upon returning to the U.S., Gilpin worked as a makeup artist in the Dallas area before taking an apprenticeship with the Williamstown Theater Festival. A chance meeting with actress Blythe Danner resulted in Gilpin gaining some support within the industry, and it wasn't long before Gilpin's dreams were coming true with roles on television's Flesh 'n' Blood and 21 Jump Street. A role on Cheers followed shortly after, and when a spin-off series entitled Frasier became an unexpected hit, Gilpin found the role that would bring her into households across the country on a weekly basis. Appearing frequently on such made-for-television films as The Secret She Carried (1996) and Laughter on the 23rd Floor (2000) while simultaneously essaying her role on Frasier, Gilpin (who was named after the animated Disney character Peri the squirrel) has also loaned her voice to such animated projects as television's Hercules and the computer-animated feature Final Fantasy: The Spirits Within (2001). Throughout the 2000's and 2010's, Gilpin remained active, starring most notably on the dance series Make It or Break It.

Trivia: Brittany Murphy first came to the attention of film audiences as Tai, one of Alicia Silverstone's airhead friends, in the 1995 comedy Clueless. Though convincing as a dim-bulb character, Murphy cuts dramatically against this grain off-camera, as a ferociously intelligent and ambitious young performer who had acting in her blood from early childhood. As a teenager and young adult, she gave expression to the scope of her talent and versatility with a series of engaging film and television roles.Born in Atlanta on November 10, 1977, Murphy was raised by her single mother in Edison, New Jersey; she later indicated, in interviews, that her mom struggled financially - that they were forced to eat spaghetti night after night, and that on certain occasions, she had to beg her mother to buy clothes at KMart; this would later account for Murphy's marked social investment in homeless causes, as discussed in a February 2003 Glamour article.A precocious child who began putting on shows when she was a toddler, Murphy was acting in regional theatre productions by the age of nine. Work in various commercials followed, and in 1990 she landed her first television appearance at the age of twelve, on the sitcom Blossom. She also secured a supporting role as Brenda Drexell, the fourteen-year-old daughter of Dabney Coleman's fifth grade teacher Otis Drexell, on the (mercifully) short-lived 1991 FOX sitcom Drexell's Class. The following year, Murphy took her first cinematic bow in the dysfunctional family drama Family Prayers. Murphy's talent for portraying, dramatically, all degrees on the spectrum of behavioral dysfunction further came to light in three successive projects through 1999: the blackly comic Reese Witherspoon trailer trash odyssey Freeway (1996) (as a disfigured lesbian who befriends Witherspoon's Vanessa); a mental patient in Lloyd Kramer's made-for-TV David and Lisa (1998), and James Mangold's Girl, Interrupted (1999) (as yet another resident at a mental institution).Meanwhile, on a less ambitious (albeit more whimsical) note, Murphy also became a fixtureon King of the Hill, Mike Judge's long-running contemporary cartoon of suburban life in the southern U.S., as Luanne Platter, the hair stylist niece who comes to live with Hank Hill's family. Murphy kept a full plate as the millennium wrapped. In addition to her work for Mangold in 1999,she also explored the collective insanity of the beauty pageant world in Drop Dead Gorgeous, while on the small screen, she covered much darker thematic ground with the well-received Holocaust drama The Devil's Arithmetic (also 1999). In 2001, Murphy appeared in the Michael Douglas thriller Don't Say a Word, and alongside Drew Barrymore in Riding in Cars With Boys.Cast opposite Eminem in director Curtis Hanson's 2002 drama 8 Mile, Murphy performed compellingly as an aspiring rap star's unapologetic muse; in 2004, Murphy headlined Nick Hurran's thoroughly disappointing rom-com Little Black Book. She also made a splash in Robert Rodriguez's innovative graphic novel adaptation Sin City, as the arrogant waitress who becomes the prize in a heated rivalry between Benicio del Toro and Clive Owen. Murphy made appearances in four features in 2006. In Alex Keshishian's progressive romantic comedy Love and Other Disasters, she played a London-based American expatriate, employed at Vogue, who tries to fix up her gay roommate; in Ed Burns's sixth directorial outing, the Big Chill-like romantic comedy The Groomsmen, she played the expectant girlfriend of Burns's Paulie. She also portrayed a member of the ensemble in Karen Moncrieff's murder mystery The Dead Girl, about a group of seemingly disconnected individuals whose lives intersect as a girl's murderer comes to light, and one of the lead voices in George "Babe" Miller's Happy Feet, an animated penguin tale.Murphy's appearance alongside Ashton Kutcher in Just Married was - to some degree - a case of art imitating life: offscreen, Murphy and Kutcher began to date as well (and became a hot tabloid item), though unlike their onscreen counterparts, they never wed.In the several years that followed, Murphy remained active, both in front of and behind the camera; she lent her voice to the CG-animated George Miller comedy Happy Feet (2006), and starred in and produced a Robert Allan Ackerman directed comedy-drama, The Ramen Girl, that suggested tremendous promise (though it went straight to home video). Murphy also starred in a made-for-television movie on the Lifetime network, Nora Roberts' Tribute (2009). That marked the end of her career, however: the actress's life was tragically cut short when she died in December 2009 at the age of 32.

Trivia: Actress/screenwriter Valerie Curtin began her acting career on the New York stage, making her film bow as Vera in 1975's Alice Doesn't Live Here Anymore. Seldom rising above the supporting-player ranks, Curtin has been more artistically satisfied by her scriptwriting work, winning an Oscar nomination for 1979's ...And Justice For All. This project, like many others, was a collaborative effort between Curtin and her director/writer husband Barry Levinson. Valerie Curtin's TV work has included a season as a regular on the comedy variety series The Jim Stafford Show (1975), and the regular role of Judy Bernley on the 1982 sitcom version of the feature film 9 to 5 (the same role played by Jane Fonda in the original movie). Curtin is the daughter of Joseph Curtin, a radio actor best known for his portrayal of Nick Charles on The Adventures of the Thin Man and of Peter Galway on the daytime serial Our Gal Sunday. She is also the cousin of Saturday Night Live veteran Jane Curtin.

Trivia: Blue-eyed British actor Malcolm McDowell has a history of playing angry, cruel characters that still managed to be charming. Born in working-class Leeds, England, he sold coffee around Yorkshire before joining the Royal Shakespeare Company in the late '60s. By 1967, he had made his big-screen debut in Poor Cow, the first feature-length film from director Ken Loach. Moving to New York, McDowell met director Lindsay Anderson and appeared in his off-Broadway production of Look Back in Anger. (He would reprise his role of angry young man Jimmy Porter in the 1980 film version.) He then played Mick Travis, the rebellious boarding school student in If.... (1968), a role he would continue in Anderson's next two films, O Lucky Man! (which he co-wrote) and Britannia Hospital (1982). Director Stanley Kubrick took notice of his work with Anderson and gave McDowell his international breakthrough with A Clockwork Orange, based upon the novel by Anthony Burgess. His portrayal of the sadistic Alex earned him two Best Actor nominations, but also cemented a dark image that would persist throughout his career. He would occasionally get breaks with characters such as Captain Flashman, the hero in the adventure satire Royal Flash or the naïve fighter in the WWI drama Aces High. But his unscrupulous reputation was reinforced in 1979, when he starred in the title role as the Roman emperor in Bob Guccione's notorious production of Caligula. He made his first American film the same year, playing H.G. Wells in Time After Time alongside young actress Mary Steenburgen (they were married from 1980-1990). McDowell went on to star in the horror remake Cat People, the action-adventure Blue Thunder, and the rock musical-comedy Get Crazy. McDowell made several TV movies toward the late '80s, including Gulag, Arthur the King, and Monte Carlo. After a serious bout with a persistent drug problem, his hair turned white and he started playing regular villains in largely forgettable U.S. releases. He had better casting luck abroad, such as the leading role in the Russian film Assassin of the Tsar. After a cameo in The Player in 1992, the actor started lending his voice talent to cartoons, including Captain Planet and the Planeteers, Superman, Spider-Man, Batman: The Animated Series, Biker Mice From Mars, and the features The Fist of the North Star and Happily Ever After. He also provided the voice of Commodore Geoffrey Tolwyn for the Wing Commander video game series and subsequent cartoon. His villainous roles started to gravitate toward science fiction with Tank Girl, Cyborg 3: The Recycler, and, most notably, Dr. Soran in Star Trek: Generations. On television, he played the evil Benny Barrett on the BBC series Our Friends in the North and the sinister Mr. Roarke on the ABC revival series Fantasy Island. In the late '90s, he appeared in a lot of direct-to-video and made-for-cable movies before making a return to U.K. theatrical features with the family drama My Life So Far in 1999 and Gangster No. 1 in 2000. In 2003, he appeared in the horseracing film Hidalgo, Robert Altman's The Company, and the Russian film Evilenko as serial killer Andrei Chikatilo. For better or worse, McDowell's most recognizable role of the decade would likely be that of Dr. Samuel Loomis in Rob Zombie's Halloween (2008) and its 2009 sequel -- thouigh a recurring role on the NBC hit Heroes certainly didn't hurt in boosting his exposure among viewers too young to remember his dramatic defining roles. Occasional voice work in The Disney Channel's Phineas and Ferb continued that trend - albiet in a less conspicuous manner -- then in 2011 the screen veteran turned in a brief but memorable performance in Michel Hazanavicius' Oscar favorite The Artist, proving that even without so much as a line of dialogue, McDowell still had the charisma to command the screen.