Los Angeles Rams (6-2) at San Francisco 49ers (6-3). From Levi's Stadium. A pivotal collision between NFC West heavyweights finds Sean McVay's Rams eager to avenge a 26-23 overtime home loss from Week 4 that ended with Kyren Williams stuffed on 4th-and-1 (with L.A. in field goal range). Bryce Huff heads the pass rush for an injury-plagued Niners defense, while Mac Jones is 5-2 as starting QB.