Arizona Cardinals (3-5) at Seattle Seahawks (6-2). From Lumen Field. Mike Macdonald's unflappable NFC West-co-leading Seahawks bid for a ninth straight win over Arizona, which fell 23-20 in the first meeting in Week 4. Even with myriad injuries, the Seattle defense has held firm, allowing just 270 ypg in its six wins. DeMarcus Lawrence leads the pursuit of Cards QB Jacoby Brissett (6 TDs, 1 INT).