When faced with an incurable, debilitating and progressive disease, you have a choice to make. How do you live your life? When Jeffrey McElfresh was a child, his feet and hands were gradually losing function. At age 41, he finally learned the name of his malady: Charcot-Marie-Tooth disease, a rare peripheral neuropathy that disrupts signals from the brain, causing muscles in the feet and hands to atrophy.