Trivia: For better or worse, leading actor Kelsey Grammer's name will probably forever be associated with the pompous, garrulous, and self-absorbed but lovable psychiatrist Frasier Crane, a character Grammer has played on television since he first appeared on the NBC sitcom Cheers, in 1984, as a love interest for Shelley Long. Though Frasier was not intended to become a series regular, Grammer's performance of the blowhard neurotic charmed audiences and he remained with Cheers through its 1993 demise. At the beginning of the 1993-1994 television season, Grammer's character was resurrected in his own show and moved from Boston to Seattle, where he became a radio psychologist and faced a whole slew of folks just waiting to poke metaphorical pins in his hot air balloon. Thanks to excellent performances and top-notch writing, Frasier became as big a hit as its predecessor. Grammer won three Emmy awards and was nominated for seven more (twice for Cheers, once for his guest appearance on a 1992 episode of Wings, four times for Frasier) for playing the character. Born on St. Thomas, one of the U.S. Virgin Islands, Grammer knew extreme tragedy in youth. Following the shooting death of his father when he was a boy, he was raised in New Jersey and then Florida, by his mother and grandfather. His grandfather died before Grammer became a teen. When he was 20, his sister was abducted and violently murdered. Five years later, he lost two half brothers in a diving accident. As a young man, Grammer found comfort in Shakespeare; with his acting debut in a high school production of The Little Foxes came an interest in pursuing drama as a career. He enrolled in Juilliard, but dropped out after two years to work at San Diego's Old Globe Theater, where he gained three years' invaluable experience performing in Shakespearean and classical dramas; afterward, Grammer performed in productions across the country. He eventually made it to Broadway, where he appeared in various productions, including Othello. Prior to playing Frasier, Grammer appeared occasionally on television and had regular roles in three soap operas, including One Life to Live. He continues to occasionally guest star on other series. Fans of the animated satire The Simpsons will recognize his periodic voice characterization as the venomous Sideshow Bob. Miniseries and telemovies in which he has appeared include London Suite and Beyond Suspicion. Grammer made his feature film debut with a small role in Top of the Hill (1989) and had his first starring role in the much-panned comedy Down Periscope (1996). In addition to his Emmy kudos, Grammer has received an American Comedy Award, two Golden Globes, and a People's Choice Award. In 1995, he published his autobiography So Far.Grammer would spend the following years taking on TV roles on shows like Back to You and Boss, but would find even more success as a producer, helping bring shows like The Game, Girlfriends, Hank, Medium, and World Cup Comedy to fruition. In 2014, he returned to acting in a big way, making a cameo appearance in X-Men: Days of Future Past, reprising his role as Beast, playing the bad guy in Transformers: Age of Extinction, and returning to television in the FX series Partners.

Trivia: Although he is best known for his role as anal-retentive psychiatrist extraordinaire Niles Crane on the celebrated sitcom Frasier, David Hyde Pierce has also done considerable work on the stage and screen. Fair, birdlike, and bearing an uncanny resemblance to Frasier co-star Kelsey Grammer, Pierce is one of the entertainment business' finest purveyors of a certain kind of blue-blooded neuroticism, and, in the eyes of some viewers, has even gone so far as to make insecurity perversely sexy.Born in Saratoga Springs, New York, on April 3, 1959, Pierce was raised in what he has described as a "very run-of-the-mill, middle-class" household. When he was eight, he began taking piano lessons, and he decided to pursue a career as a concert pianist. He continued to train until he got to Yale University, where he realized that he was better suited to the acting profession. Following graduation, Pierce moved to New York and did a brief stint as a tie salesman at Bloomingdale's before being cast in a Broadway play. Although the production was a flop, Pierce continued to work on the stage in New York and Chicago for several years and was eventually cast as a suicidal congressman on the short-lived sitcom The Powers That Be in 1992. His work on the show, coupled with his resemblance to Kelsey Grammer, led to his casting on Frasier the following year.Frasier proved to be the turning point in Pierce's career. His portrayal of Niles, aside from winning him a slew of awards, including an Emmy, also provided a number of opportunities for the actor on the big screen. Pierce, who had been acting sporadically in films since the early '80s, could be seen in supporting roles in such '90s films as Sleepless in Seattle (1993), Nixon (1995), in which he played John Dean, and the animated A Bug's Life (1998), for which he provided the voice of a stick insect.As the first decade of the 21st century opened, Pierce began appearing in more and more feature films, selecting an eclectic array of roles that utitlized his strengths without resorting to rehashing the Niles Crane character. Diverse in their genre and theme, the projects also ranged in their levels of success and acclaim. The 2000 comedy Isn't She Great was an abysmal failure, while the indie films Wet Hot American Summer and Full Frontal both left audiences and critics fiercely split. Pierce also continued to flex his voice skills in the animated features Osmosis Jones and Treasure Planet.One of Pierce's best-received roles came in 2003, when he costarred in the tongue-in-cheek comedy Down With Love. While not much of a box-office hit, the film managed to charm many critics with its wall-to-wall homages to 1960s sex-comedies. A year later, Pierce again showed up sans-body, providing the voice of Abe Sapien in the comic-book adaptation Hellboy. He reunited with Hellboy creator Mike Mignola's animated comic adaptation The Amazing Screw-On Head to voice the role of the dreaded Emperor Zombie in 2006, and joined the cast of The Perfect Host in 2010 for a leading role as Warwick Wilson, whose genteel façade hides a deep rage and mental instability.

Trivia: A distinctive-looking, grey-haired British character actor, John Mahoney worked onstage in his teens, and moved to the U.S. at 19. In his mid-30s, while employed as an editor in Chicago, he decided to renew his interest in acting, and he enrolled in classes at a local theater co-founded by playwright David Mamet; he landed a role in a Mamet play and left his job for the part. At the urging of actor John Malkovich, he went on to join Chicago's celebrated Steppenwolf Theater; eventually he appeared in more than 30 plays. For his work in the Broadway play House of Blue Leaves he won a Tony and a Clarence Derwent Award. For his work in the lead role of Orphans (on Broadway and in Chicago) he won a Theater World Award. He still lives in Chicago, and maintains his connection with Steppenwolf. Mahoney debuted onscreen in Mission HIll (1982), but his screen breakthrough came in his fifth film, Barry Levinson's popular comedy Tin Men (1987); afterwards he went on to better parts in more noteworthy movies, and has avoided typecasting in a busy screen career. Mahoney's TV credits include Favorite Son and House of Blue Leaves, in which he reprised his stage role; he has since achieved wide popularity as Martin Crane, Frasier Crane's crochety father, on the NBC sitcom Frasier.

Trivia: Began studying ballet at a very early age, but hurt her ankle when she was 18 and was forced to give it up. Appeared in David Lee Roth's video for "California Girls." Lived for a time with her best friend Faith Ford, whom she met in acting class. Cofounded the production company Bristol Cities with Frasier costar Peri Gilpin in 1998. Since her first pregnancy wasn't written into Frasier, her character, Daphne, was sent off to a fat camp and was said to have lost 9 pounds, 12 ounces---the weight of Jane's daughter when she was born. Made her Broadway debut in Cabaret as Sally Bowles in 2002. Reunited with Fraiser alum Wendy Malick to costar in the TV Land sitcom Hot in Cleveland.

Trivia: With a father who was a famous local radio and television celebrity, a model mother who appeared in television, and a working relationship with Wings producer Roz Doyle in her past, it may all seem like an obscure cosmic joke that pretty Peri Gilpin would rise to fame as radio producer Roz Doyle on the smash television sitcom Frasier, though the longtime actress would likely credit her success to hard work rather than astrological coincidence.Born in Waco, TX, and raised in Dallas, Gilpin began acting on stage with the Dallas Theater Company at the age of eight, a fact that helped her shake stage fright and gain the confidence that would accompany her through numerous future auditions. A Skyline High School graduate, Gilpin later studied acting at both the University of Texas at Austin and London's British-American Academy. Upon returning to the U.S., Gilpin worked as a makeup artist in the Dallas area before taking an apprenticeship with the Williamstown Theater Festival. A chance meeting with actress Blythe Danner resulted in Gilpin gaining some support within the industry, and it wasn't long before Gilpin's dreams were coming true with roles on television's Flesh 'n' Blood and 21 Jump Street. A role on Cheers followed shortly after, and when a spin-off series entitled Frasier became an unexpected hit, Gilpin found the role that would bring her into households across the country on a weekly basis. Appearing frequently on such made-for-television films as The Secret She Carried (1996) and Laughter on the 23rd Floor (2000) while simultaneously essaying her role on Frasier, Gilpin (who was named after the animated Disney character Peri the squirrel) has also loaned her voice to such animated projects as television's Hercules and the computer-animated feature Final Fantasy: The Spirits Within (2001). Throughout the 2000's and 2010's, Gilpin remained active, starring most notably on the dance series Make It or Break It.

Trivia: Specializing in playing fanatical or neurotic women, character actress Estelle Parsons has found success on stage, screen, and television, particularly in the latter venue where she is best remembered for playing Roseanne Arnold's screechy, lunatic mother on Roseanne (1988-1997). In show business, Parsons started out as a production assistant and then a staff writer on NBC's Today show, where she was eventually promoted to feature producer.Parsons launched her acting career on-stage in the late '50s. She went on to appear on and off-Broadway and in stock theater, specializing in satirical reviews. The actress made her film debut with a small role in Ladybug, Ladybug (1963). Four years later, she won an Oscar for her portrayal as Blanche in Bonnie and Clyde (1967). She earned a second Oscar nomination for playing a religious fanatic in Rachel, Rachel the following year. Parsons has appeared in many made-for-television movies, notably The UFO Incident (1977), in which she played a woman convinced that she and her husband (played by James Earl Jones) had been abducted by aliens. But for her long stint as a semi-regular on Roseanne, Parsons prefers the stage; her film and television appearances remain sporadic.

Trivia: While savvy television viewers will no doubt recognize prolific small-screen actress Wendie Malick from such popular series as Baywatch, Just Shoot Me, and HBO's smart and sexy comedy Dream On, the late '90s found her feature career warming up in such independent efforts as Manna From Heaven (2001) and Bathroom Boy (2003). A native of Buffalo, NY, who first found work in front of the cameras as a Wilhelmina model in the 1970s, the Ohio Wesleyan University alum would later work for New York congressman Jack Kemp following her graduation. Subsequently gracing the catwalks of New York, Paris, and Madrid, it was a small role in the 1978 comedy How to Pick up Girls that provided the aspiring actress with her first screen break. Though she would appear in a few theatrical releases such as Scrooged (1988) during the 1980s, most of her work came with made-for-television features and such series as Kate and Allie and Anything But Love. Increasingly visible on the small screen during the 1990s, Malick's role as series protagonist Martin Tupper's (Brian Benben) ex-wife on Dream On utilized her comic abilities to maximum effect and netted the actress four Cable ACE awards. Following the final episode of Dream On in 1996, it was only one short year before Malick began a stint on another popular series that would gain her accolades among sitcom junkies, Just Shoot Me. Her background in the modeling industry provided the ideal foundation for her role as former model Nina Van Horn, and Malick (Emmy-nominated for the role) remained with the show until its final episode in 2003, simultaneously taking occasional parts in both made-for-TV and theatrical features. In 1997 Malick took the lead in the little-seen romantic comedy Just Add Love, and following voice work as the egotistical principal in the Disney series Fillmore!, she appeared alongside Valerie Bertinelli, Jane Leeves, and Betty White the Emmy-winning comedy series Hot in Cleveland. In addition to her screen work, Wendie Malick met husband Richard Erickson while building homes for poor families in Mexico, and she also helps the homeless with her work for the Adopt-A-Family organization.

Trivia: Perhaps the ultimate thinking man's sex symbol, Helen Mirren is also one of the most respected actresses of British stage, screen, and television. With classical training, years of work on the London stage, an acclaimed television series, and dozens of films to her name, Mirren has proven herself an actress of talent, versatility, and unforgettable presence.Born Ilynea Lydia Mironoff on July 26, 1945, in London, Mirren is a descendant of the White Russian nobility. Her father was a member of an aristocratic Russian military family who came to England during the Russian Revolution, but while Mirren was growing up, he worked in turn as a violinist with the London Philharmonic, a taxi driver, and a driving instructor. His daughter, on the other hand, knew her true calling by the age of six, when she realized she wanted to become an actress, in the "old-fashioned and traditional sense." After trying to please her parents with a stint at a teacher's college, Mirren joined the National Youth Theatre, where she first made her mark playing Cleopatra. The acclaim for her performance led the way to other work, and she was soon a member of the vaunted Royal Shakespeare Company, with whom she performed a wide range of classics. Her stage career thriving, Mirren made her screen debut in 1968 in the somewhat forgettable Herostratus. The same year, she made a more auspicious appearance as Hermia in Peter Hall's lauded adaptation of A Midsummer Night's Dream, and her screen career soon took off. She worked steadily throughout the late '60s and '70s, starring in 1969's Age of Consent and working with such directors as Robert Altman on The Long Goodbye (1973) and Lindsay Anderson on O Lucky Man! (also 1973). In 1977, Mirren earned permanent notoriety for her work in Caligula, a mainstream porn offering from the powers at Penthouse that also starred such notables as Peter O'Toole, John Gielgud, and Malcolm McDowell.During the subsequent decade, Mirren continued to work on the stage, and she also broadened her cinematic resumé and fan base with such films as Excalibur (1981) and Cal (1984). Her portrayal of an older woman in love with a younger man in the latter film earned her a Best Actress award at the Cannes Film Festival and further established her reputation as an actress willing to explore the kind of unconventional relationships often ignored on the screen. The actress' willingness go beyond safe conventionality was demonstrated with her work in such films as The Mosquito Coast (1986), Pascali's Island (1988), The Cook, the Thief, His Wife and Her Lover (1989), and The Comfort of Strangers (1991). She again took on the role of an older woman in love with a younger man in Where Angels Fear to Tread in 1991, proving that seven years after Cal, her powers of attraction had been in no way tempered by time.At the beginning of the 1990s, Mirren began appearing on the television series Prime Suspect. Her character, Jane Tennison, a hard-boiled detective, proved immensely popular with viewers and critics alike, and she stayed with the series for its seven incarnations. Mirren also continued to do acclaimed work for the stage and screen, earning a Cannes Best Actress award and Oscar and BAFTA nominations for her work in The Madness of King George in 1994, and making her Broadway debut in Turgenev's A Month in the Country in 1995. The following year, she earned further acclaim for her work in Some Mother's Son, in which she played the mother of a Belfast prison hunger striker. In 1997, Mirren found the time to marry producer/director Taylor Hackford before signing on to provide the voice of the Queen in the Disney animated film The Prince of Egypt (1998). In 1999, she played the titular teacher in Kevin Williamson's disappointing Teaching Mrs. Tingle, earning the only good reviews given the movie, and she again won over critics with her title role in the made-for-television The Passion of Ayn Rand, earning an Emmy for her performance. Back on the big screen, Mirren continued with a lighthearted role as a master gardener in Greenfingers (2000), turned up in director Hal Hartley's comic monster fable No Such Thing (2001) and earned her second Oscar nomination for her re-teaming with Altman in the director's acclaimed comedy Gosford Park (2001).This pattern solidified for Mirren as her career moved through the new millennium. She was well received for her performance in yet another quirky British sleeper in 2003, with Calendar Girls. In it she played a middle-aged woman who raises money (as well as eyebrows) for a Women's Institute by posing nude with her peers. She also made notable appearances in movies like the thriller The Clearing (2004) and the romantic comedy Raising Helen (2004), before awing audiences with a performance in Shadowboxer (2005) as an assassin who is diagnosed with terminal cancer. 2005 would prove to be a special year for Mirren as September of that year would kick off a full 12 months of nonstop praise and excitement. Two of Mirren's projects would emerge during this period that would usher her into the upper tier of cinema's lead actresses -- a place that critics and fans had known she belonged all along. Coincidentally, these two projects would find her playing two different English monarchs who shared the same name. First, her performance as Queen Elizabeth I in the BBC miniseries Elizabeth I aired in September 2005, blowing viewers away with her ability to convey the full power and command of perhaps the most important crowned head in British history, all while confined to the small screen. Immersing herself into the opulent 16th century costumes and sets, Mirren tackled the Virgin Queen as a leader, a woman, and a human being, leaving such an impression that the miniseries was later aired in the U.S. By September 2006, the commotion over Mirren's performance had died down just enough for her to make an even bigger splash with her acclaimed role as Queen Elizabeth II in Stephen Frears' film The Queen. Despite the shared name, playing the modern-day figure was as different from her earlier role as it could be. Taking place in 1997 after the death of the globally beloved Princess Diana -- whose divorce from Prince Charles had been a source of epic tabloid controversy -- The Queen found Mirren playing a monarch who wielded little-to-no executive power, but whose title derived all its meaning from tradition, symbolism, and national pride. Mirren handled this queen with gentle attention to detail, following her on confused journeys both personal and in the national consciousness, showing her surprise and bewilderment as the stoic exterior on which a queen's public face had always been built suddenly caused her to be reviled. Mirren's two Elizabeths were both honored with Golden Globe wins, one for Best Actress in a Drama, and one for Best Actress in a TV Movie or Mini-Series. She was further rewarded for her efforts by capturing the Oscar for Best Actress in The Queen.In the next year she appeared in the blockbuster sequel National Treasure: Book of Secrets, but in 2009 she starred opposite Christopher Plummer in The Last Station as the wife of the dying Leo Tolstoy. For her work in that drama Mirren garnered acting nominations from the Screen Actors Guild, the Independent Spirit Awards, and the Academy. Substantial roles continued to rack up honors and acclaim for the actress in 2010, as she played an intriguing role as a former Mossad agent in The Debt, and no-longer-retired secret agent in Red, and none other than the leading role in William Shakespeare's The Tempest - with the gender of the part changed to female. Mirren would then make a comic turn in the 2011 remake of Arthur alongside British comedian Russell Brand, before delving back into drama once more with the reflective 2012 film The Door.