Trivia: For better or worse, leading actor Kelsey Grammer's name will probably forever be associated with the pompous, garrulous, and self-absorbed but lovable psychiatrist Frasier Crane, a character Grammer has played on television since he first appeared on the NBC sitcom Cheers, in 1984, as a love interest for Shelley Long. Though Frasier was not intended to become a series regular, Grammer's performance of the blowhard neurotic charmed audiences and he remained with Cheers through its 1993 demise. At the beginning of the 1993-1994 television season, Grammer's character was resurrected in his own show and moved from Boston to Seattle, where he became a radio psychologist and faced a whole slew of folks just waiting to poke metaphorical pins in his hot air balloon. Thanks to excellent performances and top-notch writing, Frasier became as big a hit as its predecessor. Grammer won three Emmy awards and was nominated for seven more (twice for Cheers, once for his guest appearance on a 1992 episode of Wings, four times for Frasier) for playing the character. Born on St. Thomas, one of the U.S. Virgin Islands, Grammer knew extreme tragedy in youth. Following the shooting death of his father when he was a boy, he was raised in New Jersey and then Florida, by his mother and grandfather. His grandfather died before Grammer became a teen. When he was 20, his sister was abducted and violently murdered. Five years later, he lost two half brothers in a diving accident. As a young man, Grammer found comfort in Shakespeare; with his acting debut in a high school production of The Little Foxes came an interest in pursuing drama as a career. He enrolled in Juilliard, but dropped out after two years to work at San Diego's Old Globe Theater, where he gained three years' invaluable experience performing in Shakespearean and classical dramas; afterward, Grammer performed in productions across the country. He eventually made it to Broadway, where he appeared in various productions, including Othello. Prior to playing Frasier, Grammer appeared occasionally on television and had regular roles in three soap operas, including One Life to Live. He continues to occasionally guest star on other series. Fans of the animated satire The Simpsons will recognize his periodic voice characterization as the venomous Sideshow Bob. Miniseries and telemovies in which he has appeared include London Suite and Beyond Suspicion. Grammer made his feature film debut with a small role in Top of the Hill (1989) and had his first starring role in the much-panned comedy Down Periscope (1996). In addition to his Emmy kudos, Grammer has received an American Comedy Award, two Golden Globes, and a People's Choice Award. In 1995, he published his autobiography So Far.Grammer would spend the following years taking on TV roles on shows like Back to You and Boss, but would find even more success as a producer, helping bring shows like The Game, Girlfriends, Hank, Medium, and World Cup Comedy to fruition. In 2014, he returned to acting in a big way, making a cameo appearance in X-Men: Days of Future Past, reprising his role as Beast, playing the bad guy in Transformers: Age of Extinction, and returning to television in the FX series Partners.

Trivia: Although he is best known for his role as anal-retentive psychiatrist extraordinaire Niles Crane on the celebrated sitcom Frasier, David Hyde Pierce has also done considerable work on the stage and screen. Fair, birdlike, and bearing an uncanny resemblance to Frasier co-star Kelsey Grammer, Pierce is one of the entertainment business' finest purveyors of a certain kind of blue-blooded neuroticism, and, in the eyes of some viewers, has even gone so far as to make insecurity perversely sexy.Born in Saratoga Springs, New York, on April 3, 1959, Pierce was raised in what he has described as a "very run-of-the-mill, middle-class" household. When he was eight, he began taking piano lessons, and he decided to pursue a career as a concert pianist. He continued to train until he got to Yale University, where he realized that he was better suited to the acting profession. Following graduation, Pierce moved to New York and did a brief stint as a tie salesman at Bloomingdale's before being cast in a Broadway play. Although the production was a flop, Pierce continued to work on the stage in New York and Chicago for several years and was eventually cast as a suicidal congressman on the short-lived sitcom The Powers That Be in 1992. His work on the show, coupled with his resemblance to Kelsey Grammer, led to his casting on Frasier the following year.Frasier proved to be the turning point in Pierce's career. His portrayal of Niles, aside from winning him a slew of awards, including an Emmy, also provided a number of opportunities for the actor on the big screen. Pierce, who had been acting sporadically in films since the early '80s, could be seen in supporting roles in such '90s films as Sleepless in Seattle (1993), Nixon (1995), in which he played John Dean, and the animated A Bug's Life (1998), for which he provided the voice of a stick insect.As the first decade of the 21st century opened, Pierce began appearing in more and more feature films, selecting an eclectic array of roles that utitlized his strengths without resorting to rehashing the Niles Crane character. Diverse in their genre and theme, the projects also ranged in their levels of success and acclaim. The 2000 comedy Isn't She Great was an abysmal failure, while the indie films Wet Hot American Summer and Full Frontal both left audiences and critics fiercely split. Pierce also continued to flex his voice skills in the animated features Osmosis Jones and Treasure Planet.One of Pierce's best-received roles came in 2003, when he costarred in the tongue-in-cheek comedy Down With Love. While not much of a box-office hit, the film managed to charm many critics with its wall-to-wall homages to 1960s sex-comedies. A year later, Pierce again showed up sans-body, providing the voice of Abe Sapien in the comic-book adaptation Hellboy. He reunited with Hellboy creator Mike Mignola's animated comic adaptation The Amazing Screw-On Head to voice the role of the dreaded Emperor Zombie in 2006, and joined the cast of The Perfect Host in 2010 for a leading role as Warwick Wilson, whose genteel façade hides a deep rage and mental instability.

Trivia: A distinctive-looking, grey-haired British character actor, John Mahoney worked onstage in his teens, and moved to the U.S. at 19. In his mid-30s, while employed as an editor in Chicago, he decided to renew his interest in acting, and he enrolled in classes at a local theater co-founded by playwright David Mamet; he landed a role in a Mamet play and left his job for the part. At the urging of actor John Malkovich, he went on to join Chicago's celebrated Steppenwolf Theater; eventually he appeared in more than 30 plays. For his work in the Broadway play House of Blue Leaves he won a Tony and a Clarence Derwent Award. For his work in the lead role of Orphans (on Broadway and in Chicago) he won a Theater World Award. He still lives in Chicago, and maintains his connection with Steppenwolf. Mahoney debuted onscreen in Mission HIll (1982), but his screen breakthrough came in his fifth film, Barry Levinson's popular comedy Tin Men (1987); afterwards he went on to better parts in more noteworthy movies, and has avoided typecasting in a busy screen career. Mahoney's TV credits include Favorite Son and House of Blue Leaves, in which he reprised his stage role; he has since achieved wide popularity as Martin Crane, Frasier Crane's crochety father, on the NBC sitcom Frasier.

Trivia: Began studying ballet at a very early age, but hurt her ankle when she was 18 and was forced to give it up. Appeared in David Lee Roth's video for "California Girls." Lived for a time with her best friend Faith Ford, whom she met in acting class. Cofounded the production company Bristol Cities with Frasier costar Peri Gilpin in 1998. Since her first pregnancy wasn't written into Frasier, her character, Daphne, was sent off to a fat camp and was said to have lost 9 pounds, 12 ounces---the weight of Jane's daughter when she was born. Made her Broadway debut in Cabaret as Sally Bowles in 2002. Reunited with Fraiser alum Wendy Malick to costar in the TV Land sitcom Hot in Cleveland.

Trivia: With a father who was a famous local radio and television celebrity, a model mother who appeared in television, and a working relationship with Wings producer Roz Doyle in her past, it may all seem like an obscure cosmic joke that pretty Peri Gilpin would rise to fame as radio producer Roz Doyle on the smash television sitcom Frasier, though the longtime actress would likely credit her success to hard work rather than astrological coincidence.Born in Waco, TX, and raised in Dallas, Gilpin began acting on stage with the Dallas Theater Company at the age of eight, a fact that helped her shake stage fright and gain the confidence that would accompany her through numerous future auditions. A Skyline High School graduate, Gilpin later studied acting at both the University of Texas at Austin and London's British-American Academy. Upon returning to the U.S., Gilpin worked as a makeup artist in the Dallas area before taking an apprenticeship with the Williamstown Theater Festival. A chance meeting with actress Blythe Danner resulted in Gilpin gaining some support within the industry, and it wasn't long before Gilpin's dreams were coming true with roles on television's Flesh 'n' Blood and 21 Jump Street. A role on Cheers followed shortly after, and when a spin-off series entitled Frasier became an unexpected hit, Gilpin found the role that would bring her into households across the country on a weekly basis. Appearing frequently on such made-for-television films as The Secret She Carried (1996) and Laughter on the 23rd Floor (2000) while simultaneously essaying her role on Frasier, Gilpin (who was named after the animated Disney character Peri the squirrel) has also loaned her voice to such animated projects as television's Hercules and the computer-animated feature Final Fantasy: The Spirits Within (2001). Throughout the 2000's and 2010's, Gilpin remained active, starring most notably on the dance series Make It or Break It.

Trivia: Launching her performing career in her native Tulsa, Jeanne Tripplehorn spent several years as a local radio DJ and TV host. Educated at both the University of Oklahoma and Juilliard, Born June 10th, 1963, Tripplehorn was first seen on a nationwide basis in 1991 in a supporting role in the made-for-TV movie The Perfect Tribute, a fictionalized retelling of the events leading up to Lincoln's Gettysburg Address. Many of Tripplehorn's film characterizations have ranged from mildly eccentric to deeply disturbed, thanks in great part to her breakthrough appearance as Michael Douglas' "rough sex" partner in the erotic chiller Basic Instinct (1992). She got a chance to play normal -- albeit frazzled -- as Hugh Grant's fiancée in the romantic comedy Mickey Blue Eyes (1999); in 2000, she returned to rougher territory as a lesbian gangster in Mike Figgis' experimental ensemble film Timecode. In 2006 Tripplehorn found success on the small screen for her role as Barb Henrickson, a devout Mormon who often struggles with her polygamous lifestyle, in the HBO drama series Big Love.

Trivia: Although Bob Hoskins first became widely known to American audiences as a detective assigned to investigate a cartoon rabbit in Who Framed Roger Rabbit (1988), the balding, burly actor had long been recognized in his native England as a performer of exceptional versatility, capable of playing characters from working-class toughs to Shakespearean villains.Born in Bury St. Edmunds, Suffolk, on October 26, 1942, where his mother had been sent to get away from the then-raging London Blitz, Hoskins was sent back to London with his mother when he was only two weeks old. Growing up in a solidly working-class family in post-war London, Hoskins stayed in school until he was 15, and he then abandoned formal education in favor of a string of diverse jobs. Over the course of the next ten years, he worked as a Covent Garden porter, member of the Norwegian Merchant Marines, steeplejack, plumber's assistant, banana picker, circus fire-eater, trainee accountant, and even spent time working on a kibbutz in Israel. At the age of 25, having garnered a lifetime's worth of unusual experiences, Hoskins got into acting. Hanging out at a pub one night with a friend who was auditioning for a play, he was asked to read for a part in the production. He got the part, and in the course of performing, was approached by an agent who suggested that Hoskins take up acting professionally and began arranging auditions for him. From there, Hoskins began acting onstage, working throughout the '60s, '70s, and '80s with such theatres as London's Royal Court and National Theatre and as a member of such troupes as The Royal Shakespeare Company.Hoskins made his film debut in 1972 with a minor role in the comedy Up the Front. Three years later he got his first substantial film role in the forgettable Inserts, but in 1980, he made a significant breakthrough, turning in a brilliant portrayal of a successful gangster whose world suddenly begins to fall apart in The Long Good Friday. He found even greater success six years later portraying a gangster-turned-chauffeur assigned to a high-priced call girl in Mona Lisa. His performance earned him Best Actor awards from the British Academy, the Cannes Film Festival, and the New York Film Critics Circle, and a Best Actor Academy Award nomination. For all of the acclaim surrounding his work, it was not until he starred in the aforementioned Who Framed Roger Rabbit? in 1988 that Hoskins became known to a mainstream American audience. His American accent in the film was so convincing, that in addition to earning him a Golden Globe nomination, it led some viewers to assume that he was actually an American actor.Hoskins could subsequently be seen in a number of American films in addition to those he made in Britain, appearing in such features as Mermaids (1990), in which he played Cher's love interest; Heart Condition (1990), in which he played an unhinged racist detective; and Nixon (1995), which featured him as another crazed law enforcement official, J. Edgar Hoover. In 1997, he returned to his roots in Twentyfourseven, earning a European Film Academy Best Actor Award for his portrayal of a man trying to set up an amateur boxing league for working-class young men in economically depressed, Thatcher-era England. Two years later, Hoskins turned in a similarly gripping performance as a caterer with a dangerous secret in Felicia's Journey, a psychological thriller directed by Atom Egoyan.Hoskins continued to work steadily into the beginning of the next decade in a variety of projects including acting opposite Michael Caine in Last Orders and playing a supporting role in the Jennifer Lopez romantic comedy Maid in Manhattan. He continued to appear in an eclectic series of films including Kevin Spacey's Bobby Darin biopic Beyond the Seas, as a very bad guy in the martial-arts film Unleashed, the costume drama Vanity Fair, and earning strong reviews playing opposite an Oscar nominated Judi Dench in Mrs. Henderson Presents. He also lent his very distinctive voice to one of the animated characters in the sequel Gairfield: A Tale of Two Kitties. That same year he portrayed a movie studio chief who may have had something to do with the death of George Reeves in the drama Hollywoodland opposite Ben Affleck, Adrien Brody, and Diane Lane. He appeared in Disney's A Christmas Carol, Made in Dangenham, and 2012's Snow White and the Huntsman. In addition to acting, Hoskins has worked behind the camera in a number of capacities. In 1989, he made his directorial and screenwriting debut with The Raggedy Rawney, a drama about a band of gypsies set during World War II. He also served as an executive producer for The Secret Agent in 1996.In August of 2012 Hoskins announced his retirement from acting in part because he was diagnosed with Parkinson's disease. He passed away after a bout of pneumonia in 2014, at age 71.

Trivia: An alumna of the Royal Academy of Dramatic Arts in London, actress Felicity Huffman is one of many classically trained stage performers who have found a home on television. She appeared on Broadway in David Mamet's Feed the Plow and co-founded the New York Atlantic Theater Company, along with Mamet and her husband, film actor William H. Macy. Making her feature-film debut in 1988 in Mamet's comedy drama Things Change, Huffman continued her acting career in the world of made-for-TV movies. A few exceptions include small roles in Reversal of Fortune, Hackers, The Spanish Prisoner, and Magnolia. In 1997 she won an Obie award for her work in the off-Broadway production of David Mamet's Cryptogram. Moving to the small-screen, Huffman was bumped up to starring status for the role of Dana Whitaker on the sitcom Sports Night, which ran from 1998 to 2000 on ABC before moving over to Comedy Central in syndication. She earned Golden Globe and Screen Actors Guild nominations for her work on that show. After Sports Night's cancellation in 2000, Huffman had her first child and could be seen in a string of TV movies, notably as Lady Bird Johnson in John Frankenheimer's Path to War. She then lent her voice to Disney's animated series Kim Possible and made appearances on Frasier, The West Wing, and {Girls Club. In 2003 Huffman was back to lead status as Lorna Colm on the Showtime original series Out of Order, also starring Eric Stoltz and husband Macy. Though the show was soon cancelled, it wouldn't be long before Huffman was back at it with another new show. This time around, she starred in ABC's dark primetime dramatic comedy series Desperate Housewives, which premiered in the Fall of 2004. The wildly successful series proved to be a break unlike anything the actress had ever experienced, earning her an Emmy, a Screen Actor's Guild Award, multiple Golden Globe nominations, and a stardom that finally made her a household name. In 2006, she won a Golden Globe for Best Performance by an Actress in a Motion Picture - Drama for her role in Transamerica, in which she plays a pre-op male-to-female transsexual who learns she has a teenage son from a clumsy sexual encounter during her life as a man. Huffman's critical acclaim cemented that she had arrived as an actress and would not need to rely on the notoriety of Desperate Housewives in order to maintain a vibrant career. She would spend the next several years apperaing in films like Georgia Rule, Phoebe in Wonderland, and Rudderless.

Trivia: American actress Scout Taylor-Compton debuted as an ingenue, appearing on several television series in guest and recurring roles during the 1990s and 2000s, including Charmed, ER, and Gilmore Girls. She then segued into feature roles in the mid-2000s, with memorable contributions to the Jennifer Garner-headlined age-swap fantasy 13 Going on 30, and -- later that same year -- with the all-girl teen comedy Sleepover (2004). Taylor-Compton made her biggest splash, however, by essaying the role of Laurie Strode, perpetually stalked slasher victim (and sister of Michael Myers), in Rob Zombie's much-anticipated horror remake Halloween (2007); the actress inherited the role, of course, from former scream queen Jamie Lee Curtis. Taylor-Compton also made headlines in August 2005 when officially declared "missing" from her family's Apple Valley, CA, home. She was recovered a short time later.