Trivia: For better or worse, leading actor Kelsey Grammer's name will probably forever be associated with the pompous, garrulous, and self-absorbed but lovable psychiatrist Frasier Crane, a character Grammer has played on television since he first appeared on the NBC sitcom Cheers, in 1984, as a love interest for Shelley Long. Though Frasier was not intended to become a series regular, Grammer's performance of the blowhard neurotic charmed audiences and he remained with Cheers through its 1993 demise. At the beginning of the 1993-1994 television season, Grammer's character was resurrected in his own show and moved from Boston to Seattle, where he became a radio psychologist and faced a whole slew of folks just waiting to poke metaphorical pins in his hot air balloon. Thanks to excellent performances and top-notch writing, Frasier became as big a hit as its predecessor. Grammer won three Emmy awards and was nominated for seven more (twice for Cheers, once for his guest appearance on a 1992 episode of Wings, four times for Frasier) for playing the character. Born on St. Thomas, one of the U.S. Virgin Islands, Grammer knew extreme tragedy in youth. Following the shooting death of his father when he was a boy, he was raised in New Jersey and then Florida, by his mother and grandfather. His grandfather died before Grammer became a teen. When he was 20, his sister was abducted and violently murdered. Five years later, he lost two half brothers in a diving accident. As a young man, Grammer found comfort in Shakespeare; with his acting debut in a high school production of The Little Foxes came an interest in pursuing drama as a career. He enrolled in Juilliard, but dropped out after two years to work at San Diego's Old Globe Theater, where he gained three years' invaluable experience performing in Shakespearean and classical dramas; afterward, Grammer performed in productions across the country. He eventually made it to Broadway, where he appeared in various productions, including Othello. Prior to playing Frasier, Grammer appeared occasionally on television and had regular roles in three soap operas, including One Life to Live. He continues to occasionally guest star on other series. Fans of the animated satire The Simpsons will recognize his periodic voice characterization as the venomous Sideshow Bob. Miniseries and telemovies in which he has appeared include London Suite and Beyond Suspicion. Grammer made his feature film debut with a small role in Top of the Hill (1989) and had his first starring role in the much-panned comedy Down Periscope (1996). In addition to his Emmy kudos, Grammer has received an American Comedy Award, two Golden Globes, and a People's Choice Award. In 1995, he published his autobiography So Far.Grammer would spend the following years taking on TV roles on shows like Back to You and Boss, but would find even more success as a producer, helping bring shows like The Game, Girlfriends, Hank, Medium, and World Cup Comedy to fruition. In 2014, he returned to acting in a big way, making a cameo appearance in X-Men: Days of Future Past, reprising his role as Beast, playing the bad guy in Transformers: Age of Extinction, and returning to television in the FX series Partners.

Trivia: Although he is best known for his role as anal-retentive psychiatrist extraordinaire Niles Crane on the celebrated sitcom Frasier, David Hyde Pierce has also done considerable work on the stage and screen. Fair, birdlike, and bearing an uncanny resemblance to Frasier co-star Kelsey Grammer, Pierce is one of the entertainment business' finest purveyors of a certain kind of blue-blooded neuroticism, and, in the eyes of some viewers, has even gone so far as to make insecurity perversely sexy.Born in Saratoga Springs, New York, on April 3, 1959, Pierce was raised in what he has described as a "very run-of-the-mill, middle-class" household. When he was eight, he began taking piano lessons, and he decided to pursue a career as a concert pianist. He continued to train until he got to Yale University, where he realized that he was better suited to the acting profession. Following graduation, Pierce moved to New York and did a brief stint as a tie salesman at Bloomingdale's before being cast in a Broadway play. Although the production was a flop, Pierce continued to work on the stage in New York and Chicago for several years and was eventually cast as a suicidal congressman on the short-lived sitcom The Powers That Be in 1992. His work on the show, coupled with his resemblance to Kelsey Grammer, led to his casting on Frasier the following year.Frasier proved to be the turning point in Pierce's career. His portrayal of Niles, aside from winning him a slew of awards, including an Emmy, also provided a number of opportunities for the actor on the big screen. Pierce, who had been acting sporadically in films since the early '80s, could be seen in supporting roles in such '90s films as Sleepless in Seattle (1993), Nixon (1995), in which he played John Dean, and the animated A Bug's Life (1998), for which he provided the voice of a stick insect.As the first decade of the 21st century opened, Pierce began appearing in more and more feature films, selecting an eclectic array of roles that utitlized his strengths without resorting to rehashing the Niles Crane character. Diverse in their genre and theme, the projects also ranged in their levels of success and acclaim. The 2000 comedy Isn't She Great was an abysmal failure, while the indie films Wet Hot American Summer and Full Frontal both left audiences and critics fiercely split. Pierce also continued to flex his voice skills in the animated features Osmosis Jones and Treasure Planet.One of Pierce's best-received roles came in 2003, when he costarred in the tongue-in-cheek comedy Down With Love. While not much of a box-office hit, the film managed to charm many critics with its wall-to-wall homages to 1960s sex-comedies. A year later, Pierce again showed up sans-body, providing the voice of Abe Sapien in the comic-book adaptation Hellboy. He reunited with Hellboy creator Mike Mignola's animated comic adaptation The Amazing Screw-On Head to voice the role of the dreaded Emperor Zombie in 2006, and joined the cast of The Perfect Host in 2010 for a leading role as Warwick Wilson, whose genteel façade hides a deep rage and mental instability.

Trivia: A distinctive-looking, grey-haired British character actor, John Mahoney worked onstage in his teens, and moved to the U.S. at 19. In his mid-30s, while employed as an editor in Chicago, he decided to renew his interest in acting, and he enrolled in classes at a local theater co-founded by playwright David Mamet; he landed a role in a Mamet play and left his job for the part. At the urging of actor John Malkovich, he went on to join Chicago's celebrated Steppenwolf Theater; eventually he appeared in more than 30 plays. For his work in the Broadway play House of Blue Leaves he won a Tony and a Clarence Derwent Award. For his work in the lead role of Orphans (on Broadway and in Chicago) he won a Theater World Award. He still lives in Chicago, and maintains his connection with Steppenwolf. Mahoney debuted onscreen in Mission HIll (1982), but his screen breakthrough came in his fifth film, Barry Levinson's popular comedy Tin Men (1987); afterwards he went on to better parts in more noteworthy movies, and has avoided typecasting in a busy screen career. Mahoney's TV credits include Favorite Son and House of Blue Leaves, in which he reprised his stage role; he has since achieved wide popularity as Martin Crane, Frasier Crane's crochety father, on the NBC sitcom Frasier.

Trivia: Began studying ballet at a very early age, but hurt her ankle when she was 18 and was forced to give it up. Appeared in David Lee Roth's video for "California Girls." Lived for a time with her best friend Faith Ford, whom she met in acting class. Cofounded the production company Bristol Cities with Frasier costar Peri Gilpin in 1998. Since her first pregnancy wasn't written into Frasier, her character, Daphne, was sent off to a fat camp and was said to have lost 9 pounds, 12 ounces---the weight of Jane's daughter when she was born. Made her Broadway debut in Cabaret as Sally Bowles in 2002. Reunited with Fraiser alum Wendy Malick to costar in the TV Land sitcom Hot in Cleveland.

Trivia: With a father who was a famous local radio and television celebrity, a model mother who appeared in television, and a working relationship with Wings producer Roz Doyle in her past, it may all seem like an obscure cosmic joke that pretty Peri Gilpin would rise to fame as radio producer Roz Doyle on the smash television sitcom Frasier, though the longtime actress would likely credit her success to hard work rather than astrological coincidence.Born in Waco, TX, and raised in Dallas, Gilpin began acting on stage with the Dallas Theater Company at the age of eight, a fact that helped her shake stage fright and gain the confidence that would accompany her through numerous future auditions. A Skyline High School graduate, Gilpin later studied acting at both the University of Texas at Austin and London's British-American Academy. Upon returning to the U.S., Gilpin worked as a makeup artist in the Dallas area before taking an apprenticeship with the Williamstown Theater Festival. A chance meeting with actress Blythe Danner resulted in Gilpin gaining some support within the industry, and it wasn't long before Gilpin's dreams were coming true with roles on television's Flesh 'n' Blood and 21 Jump Street. A role on Cheers followed shortly after, and when a spin-off series entitled Frasier became an unexpected hit, Gilpin found the role that would bring her into households across the country on a weekly basis. Appearing frequently on such made-for-television films as The Secret She Carried (1996) and Laughter on the 23rd Floor (2000) while simultaneously essaying her role on Frasier, Gilpin (who was named after the animated Disney character Peri the squirrel) has also loaned her voice to such animated projects as television's Hercules and the computer-animated feature Final Fantasy: The Spirits Within (2001). Throughout the 2000's and 2010's, Gilpin remained active, starring most notably on the dance series Make It or Break It.

Trivia: Trained at Juilliard and the American Academy of Dramatic Art, actress Constance Towers made her first impression on the public as a film actress. Towers was seen as the resourceful Southern-belle leading lady of John Ford's The Horse Soldiers (1959), then essayed a similar characterization in Ford's Sergeant Rutledge (1960). For a brief period in the early 1960s, she was the pet actress of director Samuel Fuller, who effectively cast her in extremely demanding roles in Shock Corridor (1963) and The Naked Kiss (1965). With several film and TV appearances to her credit, Towers finally made her professional stage debut in a 1960 production of Guys and Dolls; one year later, she made her Broadway bow as star of Anya, a musicalization of Anastasia. Most closely associated with musicals, she has made hundreds of appearances in revivals of such Rodgers and Hammerstein classics as South Pacific, The King and I, and The Sound of Music. During the 1960s and 1970s, Constance hosted a daily discussion show on New York radio station WOR. On TV, Towers has been seen as Clarissa McCandliss, daughter of JR-type patriarch Rory Calhoun, on the daytime drama Capitol (1982-87), and as Camilla, the mother of ex-call girl Jade O'Keefe (Lisa Hartman), on the heavy-breathing nighttimer 2000 Malibu Road (1992). Constance Towers is married to former actor and U.S. diplomat John Gavin.

Trivia: Actor John O'Hurley's stately voice and brilliant silver mane have earned him many notable roles, but the one he's perhaps best known for is the quirky J. Peterman on the hit sitcom Seinfeld. Playing the real man behind the iconic catalogue full of exotic items supposedly discovered by the world-traveling adventurer, O'Hurley became such a hit with fans in the small role that the character became a regular part of the series. O'Hurley's other roles have included everything from family movies to erotic thrillers, and his interests outside of acting are varied as well. He's received classical training in voice and piano, he works in the non-profit sector to raise money for epilepsy research, and after his lauded appearance on Seinfeld, he was offered the chance to buy a portion of the real J. Peterman Company, which had been in a serious financial slump, but turned a new profit the year after O'Hurley came on board.In 2005, O'Hurley competed in the first season of the hit series Dancing with the Stars and, along with his partner Charlotte Jørgensen, was the runner up in a very close finale. Controversy arose because he was so popular with the public that many fans felt the competition had been rigged in favor of the official winner, soap star Kelly Monaco. O'Hurley won the resulting dance-off, earning over a hundred thousand dollars for the charity Golfers Against Cancer. Then in 2006, he took over hosting duties for the game show Family Feud, which was beginning its 30th year on television. O'Hurley has also appeared in numerous stage productions, including the Las Vegas production of the Monty Python musical Spamalot, for which he took on the the starring role of King Arthur.

Trivia: Often noted for his comment that he enjoys working in all of his films -- as long as he doesn't have to see any of them -- actor James Spader (born February 2nd, 1960) may have missed out on seeing a few good performances in some pretty memorable films.Though descended from a long line of scholars and professors, Spader, in ironic contrast to his theatrical image as the definitive terminal yuppie, dropped out of Phillips Andover prep school to pursue a career as an actor. Forsaking his formal education, Spader instead decided to focus his attention on acting by studying at the Michael Chekhov school in New York, while also working a variety of odd jobs to support himself until he found success as a thespian. Making his debut in the 1978 comedy Team Mates, Spader began the slow process of gaining more frequent work with roles of increasing substance. Spader's first role came in Franco Zeffirelli's soft-core teen melodrama Endless Love (1981) (also notable as the debut of another young unknown actor named Tom Cruise. After a brief, mid-'80s stint in teen exploitation including Tuff Turf and The New Kids (both 1985), Spader gained mainstream recognition with his first fore in yuppiedom as Molly Ringwald's insincere suitor in Pretty in Pink (1986). Over the course of the next few years, Spader would refine his slimy persona to perfection in Wall Street (1987) and Less Than Zero (1987), and take an interesting turn as a possible serial killer in the Jack the Ripper thriller Jack's Back (1988), but it was the end of the decade that brought the defining role in Spader's career.Though his role in independent filmmaker Steven Soderbergh's voyeurism-obsessed sex, lies and videotape did little to propel his persona into more likeable territories, it showed an actor with considerable talent who wasn't afraid to take risks, winning him the Best Actor award at the 1989 Cannes Film Festival. Spader's dark portrayal of the ominously seductive videophile struck a chord in audiences and critics alike and turned him into a household name. The '90s found Spader expanding his yuppie image into more sympathetic territory with roles in White Palace and Bad Influence (both 1990), and he continued his likeable trend in the first of the mega-budget Dean Devlin/Roland Emmerich collaborations, Stargate (1994), before reverting back as Jack Nicholson's manipulative lycanthropic rival in Mike Nichols' imaginative satire Wolf (1994). Controversy soon followed with David Cronenberg's widely panned study of fetishistic alienation Crash (1996), and Spader has worked steadily since, with roles in Supernova (2000) and Speaking of Sex (2001). With the release of Secretary (2002), Spader once again found himself in the favor of art house audiences for his portrayal of a demanding lawyer who hires a recently released mental patient for the eponimous duty.Spader found success on the small screen once again for his work on Boston Legal from 2004 to 2008 as the character of Alan Moore, a vehemently moral attorney who resorts to unethical methods during his pursuit of justice (a role that would win the actor two Emmys). Spader made a guest appearance on an episode of The Office, and returned to the sitcom in 2011 as part of the main cast.