Trivia: Reagan Gomez-Preston began her onscreen career in the mid-'90s, playing Zaria Peterson on the series The Parent Hood from 1995 to 1999. Many TV appearances followed, on shows like Strong Medicine and ER, and Gomez-Preston eventually scored another starring TV role, on the series Love Inc. in 2005. The show didn't last, but the actress landed on her feet, scoring a voice-acting role on the Family Guy spin-off The Cleveland Show.

Trivia: Became interested in acting at age 8, when the manager for his actor sister, Lilly, suggested that he may also have a talent for performing. Landed his first ever audition, which was a commercial for Dunkin' Donuts. Is a celebrity Ambassador for GenerationOn, a charity that encourages young people to volunteer. Has aspirations to direct, so he prefers to shadow the directors of the shows he works on, instead of retreating to his trailer between takes.

Trivia: Animation pioneer Seth MacFarlane followed in the footsteps of Matt Groening, Trey Parker, and Matt Stone, and others by creating (at age 25!) one of the top-tiered animated series on national television. Family Guy, which debuted in 1999, preserved the sitcom-family premise of The Simpsons but upped the irreverence quotient tenfold (defying many who regarded such an accomplishment as impossible), meanwhile tossing in dozens upon dozens of off-the-cuff (and frequently risqué) references to pop culture -- citing everything from Oz to The Wizard of Oz, The $25,000 Pyramid to songs by a-ha, and thus seizing upon instant identification with Gen-X and Gen-Y viewers. Episodes, which began mundanely enough, could immediately segue, without advance notice, into music video-style montages, game-show sequences, multi-character musical production numbers, mock historical sequences, etc. The basic premise revolved around the nutty Griffin clan of Quahog, Rhode Island: obese toy manufacturer dad Peter; neurotic housewife Lois; ne'er-do-well, dim-bulb 13-year-old son Chris; the angst-ridden 16-year-old daughter Meg, and -- what really made the series bizarre and original -- Stewie, a one-year-old infant with a massive head, a genius IQ, and the verbal erudition of Rex Harrison.Family Guy found a sizeable audience and lasted for many seasons, yet reportedly suffered from a tumultuous history at Fox, where it endured repeat cancellations, numerous rerun episodes, and reemergence on different networks and in different time slots, meanwhile becoming a cult hit on DVD. In the interim, MacFarlane branched out into another animated sitcom, American Dad (2005). Family Guy eventually gained extremly solid ground, however, and soon spawned a spin-off, The Cleveland Show.

Trivia: Born in Japan and raised in Montgomery, AL, actor Glenn Howerton attended Juilliard before making his screen debut in the 2002 made-for-television feature Monday Night Mayhem. Recurring roles in That '80s Show and ER found Howerton settling into a comfortable small-screen schedule in 2002 and 2003, with supporting parts in such features as Serenity and Crank coming along just as Howerton joined the cast of the monumental FX comedy series It's Always Sunny in Philadelphia. In addition to his acting duties on the show, Howerton also served as writer, co-creator, and producer of the series. He would also take on regular roles on Unsupervised and lend his voice to The Cleveland Show.