Trivia: Animation pioneer Seth MacFarlane followed in the footsteps of Matt Groening, Trey Parker, and Matt Stone, and others by creating (at age 25!) one of the top-tiered animated series on national television. Family Guy, which debuted in 1999, preserved the sitcom-family premise of The Simpsons but upped the irreverence quotient tenfold (defying many who regarded such an accomplishment as impossible), meanwhile tossing in dozens upon dozens of off-the-cuff (and frequently risqué) references to pop culture -- citing everything from Oz to The Wizard of Oz, The $25,000 Pyramid to songs by a-ha, and thus seizing upon instant identification with Gen-X and Gen-Y viewers. Episodes, which began mundanely enough, could immediately segue, without advance notice, into music video-style montages, game-show sequences, multi-character musical production numbers, mock historical sequences, etc. The basic premise revolved around the nutty Griffin clan of Quahog, Rhode Island: obese toy manufacturer dad Peter; neurotic housewife Lois; ne'er-do-well, dim-bulb 13-year-old son Chris; the angst-ridden 16-year-old daughter Meg, and -- what really made the series bizarre and original -- Stewie, a one-year-old infant with a massive head, a genius IQ, and the verbal erudition of Rex Harrison.Family Guy found a sizeable audience and lasted for many seasons, yet reportedly suffered from a tumultuous history at Fox, where it endured repeat cancellations, numerous rerun episodes, and reemergence on different networks and in different time slots, meanwhile becoming a cult hit on DVD. In the interim, MacFarlane branched out into another animated sitcom, American Dad (2005). Family Guy eventually gained extremly solid ground, however, and soon spawned a spin-off, The Cleveland Show.

Trivia: Actress Wendy Schaal made her feature-film debut in the teen comedy Records (1978). She subsequently went on to have a sporadic film career, the highlights of which include Innerspace (1987) and The 'Burbs (1989). Though she worked steadily through the 1990s, she disappeared from screens in the 21st century, making a triumphant comeback voicing Francine Smith on the FOX animated sitcom American Dad!

Trivia: Former adolescent actor Scott Grimes first appeared onscreen at age 15 in Critters (1986).

Trivia: The younger sister of Family Guy and American Dad creator Seth MacFarlane, Rachael MacFarlane has provided a number of voices on her famous sibling's animated sitcom Family Guy, and the voice of Hayley Smith, a regular character on American Dad. Additional achievements of hers include voices for Johnny Bravo, Dexter's Laboratory, and The Grim Adventures of Billy & Mandy.

Trivia: American voice artist, standup comedian, and singer Dee Bradley Baker started gaining experience at age nine in all forms of theatrical production, including musical comedies, operas, and nonmusical plays. After college, Baker moved to Los Angeles and quickly established himself as a highly regarded voice actor on animated series, specials, and features. Baker demonstrated a particularly strong aptitude for various ethnic dialects, as well as animal, extraterrestrial, and monster characters. He voiced Louie in the 2000 feature The Trumpet of the Swan, contributed zombie moans to the 2004 Dawn of the Dead remake, and voiced creatures in small-screen programs such as Avatar: The Last Airbender, SpongeBob SquarePants, and Codename: Kids Next Door. Baker was also particularly memorable as Klaus, a talking fish with a massive libidinal drive, on the Seth MacFarlane animated series American Dad. In addition to his extensive film and television credits, Baker's vocal contributions to such popular video games as Left 4 Dead 2, Batman: The Brave and the Bold, Star Wars: The Force Unleashed II, and Diablo III helped to make him one of the busiest voice actors in Hollywood.

Trivia: American character actor Curtis Armstrong is best known in films for playing Dudley "Booger" Dawson in the Revenge of the Nerds series of feature films and TV movies. On television he is best remembered for playing Herbert Viola in the ABC series Moonlighting (1985-1989). When he was just starting out, Armstrong founded his own theater company in Michigan. He continued working in theater until 1983 when he made his film debut playing opposite Tom Cruise in Risky Business. He appeared in Revenge of the Nerds the following year. In addition to playing Booger, Armstrong appeared in other features, including The Clan of the Cave Bear (1986) and The Adventures of Huck Finn (1993). He would remain extremely active for decades to come, appearing in movies like Southland Tales and Beer for My Horses, and on shows like Boston Legal, The Closer, and Dan Vs.

Trivia: British actor Jared Harris first won recognition for his riveting portrayal of influential American pop artist Andy Warhol in the acclaimed I Shot Andy Warhol (1996). Though he is the son of esteemed British actor Richard Harris, he showed little interest in following his father's path until he was cast in a college production while attending North Carolina's Duke University during the early '80s. Following graduation, he returned to Britain and worked with the Royal Shakespeare Company for several years, before heading back to the states to appear off-Broadway. The actor made his screen debut in The Rachel Papers (1989). Following his appearances as Harvey Keitel's slightly retarded shop assistant in Smoke and its companion piece Blue in the Face (both 1995), Harris became a familiar face in American independent films, though he still made the occasional foray into mainstream films, appearing in Lost in Space in 1998. After portraying a sleazy Russian cab driver in Todd Solondz's acclaimed Happiness (1998), Harris could be seen in Michael Radford's B. Monkey, starring opposite Asia Argento, Rupert Everett, and Jonathan Rhys Myers. He went on to appear in Perfume and Igby Goes Down in the next few years. In 2003 he found himself playing one of Europe's most famous historical figures when he tackled the role of King Henry VIII in The Other Boleyn Girl. The next year he had small parts in The Day After Tomorrow and Ocean's Twelve. Although he was in the notorious flop Lady in the Water in 2006, two years later he appeared in the multiple Oscar nominated The Curious Case of Benjamin Button. In 2009 he had his most high-profile success joining the cast of the award-winning drama Mad Men as a British businessman. He was the bad guy in the second of Robert Downey Jr's Sherlock Holmes films, and played one of the important figures in American history when Steven Spielberg cast him in Lincoln as General Ulysses S. Grant.

Trivia: Even those who don't know Kevin Michael Richardson's face will frequently remember his voice. The actor's unique baritone has made him a memorable presence in many projects, including several voices on the animated series Family Guy. A classically trained performer, Richardson was one of eight students selected for the 1982 National Foundation for the Arts program, leading to a full scholarship for Syracuse University. He would go on to become a successful actor and voice actor, wracking up a long list of roles on everything from Pokemon to The New Batman Adventures. Othyer shows featuring Richardson's distinctive voice include Transformers Prime, Ultimate Spider-Man, and Green Lantern: The Animated Series. Real-life voices Richardson has portrayed include Bob Hope (in a 2006 Malcolm in the Middle episode), Bill Cosby (a number of Family Guy episodes) and Plato (PBS's Adventures From the Book of Virtues, 1996-98).