Trivia: Animation pioneer Seth MacFarlane followed in the footsteps of Matt Groening, Trey Parker, and Matt Stone, and others by creating (at age 25!) one of the top-tiered animated series on national television. Family Guy, which debuted in 1999, preserved the sitcom-family premise of The Simpsons but upped the irreverence quotient tenfold (defying many who regarded such an accomplishment as impossible), meanwhile tossing in dozens upon dozens of off-the-cuff (and frequently risqué) references to pop culture -- citing everything from Oz to The Wizard of Oz, The $25,000 Pyramid to songs by a-ha, and thus seizing upon instant identification with Gen-X and Gen-Y viewers. Episodes, which began mundanely enough, could immediately segue, without advance notice, into music video-style montages, game-show sequences, multi-character musical production numbers, mock historical sequences, etc. The basic premise revolved around the nutty Griffin clan of Quahog, Rhode Island: obese toy manufacturer dad Peter; neurotic housewife Lois; ne'er-do-well, dim-bulb 13-year-old son Chris; the angst-ridden 16-year-old daughter Meg, and -- what really made the series bizarre and original -- Stewie, a one-year-old infant with a massive head, a genius IQ, and the verbal erudition of Rex Harrison.Family Guy found a sizeable audience and lasted for many seasons, yet reportedly suffered from a tumultuous history at Fox, where it endured repeat cancellations, numerous rerun episodes, and reemergence on different networks and in different time slots, meanwhile becoming a cult hit on DVD. In the interim, MacFarlane branched out into another animated sitcom, American Dad (2005). Family Guy eventually gained extremly solid ground, however, and soon spawned a spin-off, The Cleveland Show.

Trivia: Best known for her roles as the outrageous Mrs. Swan on MADtv and devoted wife Lois on the hit Fox series Family Guy, comedic female talent Alex Borstein has been keeping busy on screens both large and small ever since appearing in a handful of Mighty Morphin' Power Rangers in the mid-'90s. Born in Highland Park, Chicago, and raised in the nearby suburb of Deerfield, Borstein moved to Los Angeles with her family in 1980 and eventually enrolled in San Francisco State University. It was there that the aspiring comic began trying her talent at improvisational theater, and shortly after graduation she would begin performing at the ACME Comedy Theatre. Small roles in The Mighty Morphin' Power Rangers and a short-lived spin-off were quick to follow, with her stint on MADtv beginning in 1997. While many fans cited her as a highlight of MADtv thanks to her outlandish characters and quick wit, Borstein was also eager to launch a film career and could frequently be seen in features such as Showtime, Bad Santa, and Catwoman. With a distinctive voice that seemed to lend itself well to animated performances, Borstein was cast as levelheaded housewife Lois on Family Guy in 1999. It was around this time that she also continued her small-screen trajectory with a handful appearances on the wildly popular family drama Gilmore Girls.In 2005, Borstein took a turn for the dramatic in the monochromatic period drama Good Night, and Good Luck, with subsequent television roles on Drawn Together and Robot Chicken serving well to balance out the seriousness of the critically acclaimed Edward R. Murrow drama. The following year, Borstein brought her popular stage show to viewers across the nation with the release of Drop Dead Gorgeous (In a Down to Earth Bombshell Sort of Way) on home video. In 2007, Borstein was paired with Good Night, and Good Luck star Jeff Daniels once again in the tense crime thriller The Lookout. As the years rolled on, Borstein would continue to remain a force on screen, appearing in movies like Killers, Dinner for Schmucks, and Ted.

Trivia: A petite actress with olive skin and pixie features, Ukrainian-born Mila Kunis became a breakout teen star on the FOX sitcom That '70s Show, playing spoiled daddy's girl Jackie Burkhardt. The rare 15-year-old actress to be cast as a 15-year-old character, Kunis also demonstrated her maturity by mastering accent-free English only a few years after immigrating. Her command of slang and teen vocal mannerisms won her work even when her appearance was not being utilized, as she voiced another all-American teen on FOX's animated envelope-pusher, Family Guy.Milena Markovna Kunis was born on August 14, 1983 in Kiev, Ukraine, then moved with her parents to Los Angeles when she was seven years old. Kunis credits listening to the simple vocabulary of Bob Barker on The Price Is Right with helping her develop a speedy fluency in English. She enrolled in acting classes at the Beverly Hills Studio, where she was discovered performing in a showcase. She quickly began appearing in commercials. Kunis filled out her early resumé with such pit stops as Honey, We Shrunk Ourselves (1997), Krippendorf's Tribe (1998), and the infamous WB ratings cellar-dweller Nick Freno: Licensed Teacher (1996). She also played a younger version of Angelina Jolie in the HBO movie Gia (1998). But it was her casting in Mark Brazill's That '70s Show that earned Kunis notice, as her petulant teen queen soon became a standout, able to range from endearing to grating. Her aggravated whining rung true enough to earn her a voice-over role on Family Guy, taking over for Lacey Chabert as Megan Griffin during the 2000 season. As the 2000's roled along, however, Kunis would seem to graduate to the ranks of adult actresses, rather than teen starlets, in seemingly the blink of an eye. Her comic turn in 2008's massively successful comedy Forgetting Sarah Marshall kicked off Kunis' new style, followed quickly by roles as a femme fatale in 2008's Max Payne, a seductive grifter in 2009's Extract, and a post apocalyptic heroine in 2010's Book of Eli. 2010 would also find her playing opposite Natalie Portman's Oscar winning performance in Darren Aronofsky's psychological thriller The Black Swan. Though her supporting role offered less opportunity to showcase her talents than her costar's did, Kunis was roundly praised for the skill and presence she brought to the production -- not to mention her commitment to transforming her body for her character, training for months in ballet -- all further cementing her reputation as a serious actress. Kunis would spend the next several years appearing in numerous projects, like Friends with Benefits, The Muppets, Ted, Oz the Great and Powerful and Jupiter Ascending, an epic space drama directed by the Wachowskis.