Trivia: Animation pioneer Seth MacFarlane followed in the footsteps of Matt Groening, Trey Parker, and Matt Stone, and others by creating (at age 25!) one of the top-tiered animated series on national television. Family Guy, which debuted in 1999, preserved the sitcom-family premise of The Simpsons but upped the irreverence quotient tenfold (defying many who regarded such an accomplishment as impossible), meanwhile tossing in dozens upon dozens of off-the-cuff (and frequently risqué) references to pop culture -- citing everything from Oz to The Wizard of Oz, The $25,000 Pyramid to songs by a-ha, and thus seizing upon instant identification with Gen-X and Gen-Y viewers. Episodes, which began mundanely enough, could immediately segue, without advance notice, into music video-style montages, game-show sequences, multi-character musical production numbers, mock historical sequences, etc. The basic premise revolved around the nutty Griffin clan of Quahog, Rhode Island: obese toy manufacturer dad Peter; neurotic housewife Lois; ne'er-do-well, dim-bulb 13-year-old son Chris; the angst-ridden 16-year-old daughter Meg, and -- what really made the series bizarre and original -- Stewie, a one-year-old infant with a massive head, a genius IQ, and the verbal erudition of Rex Harrison.Family Guy found a sizeable audience and lasted for many seasons, yet reportedly suffered from a tumultuous history at Fox, where it endured repeat cancellations, numerous rerun episodes, and reemergence on different networks and in different time slots, meanwhile becoming a cult hit on DVD. In the interim, MacFarlane branched out into another animated sitcom, American Dad (2005). Family Guy eventually gained extremly solid ground, however, and soon spawned a spin-off, The Cleveland Show.

Trivia: Actress Wendy Schaal made her feature-film debut in the teen comedy Records (1978). She subsequently went on to have a sporadic film career, the highlights of which include Innerspace (1987) and The 'Burbs (1989). Though she worked steadily through the 1990s, she disappeared from screens in the 21st century, making a triumphant comeback voicing Francine Smith on the FOX animated sitcom American Dad!

Trivia: Former adolescent actor Scott Grimes first appeared onscreen at age 15 in Critters (1986).

Trivia: The younger sister of Family Guy and American Dad creator Seth MacFarlane, Rachael MacFarlane has provided a number of voices on her famous sibling's animated sitcom Family Guy, and the voice of Hayley Smith, a regular character on American Dad. Additional achievements of hers include voices for Johnny Bravo, Dexter's Laboratory, and The Grim Adventures of Billy & Mandy.

Trivia: American voice artist, standup comedian, and singer Dee Bradley Baker started gaining experience at age nine in all forms of theatrical production, including musical comedies, operas, and nonmusical plays. After college, Baker moved to Los Angeles and quickly established himself as a highly regarded voice actor on animated series, specials, and features. Baker demonstrated a particularly strong aptitude for various ethnic dialects, as well as animal, extraterrestrial, and monster characters. He voiced Louie in the 2000 feature The Trumpet of the Swan, contributed zombie moans to the 2004 Dawn of the Dead remake, and voiced creatures in small-screen programs such as Avatar: The Last Airbender, SpongeBob SquarePants, and Codename: Kids Next Door. Baker was also particularly memorable as Klaus, a talking fish with a massive libidinal drive, on the Seth MacFarlane animated series American Dad. In addition to his extensive film and television credits, Baker's vocal contributions to such popular video games as Left 4 Dead 2, Batman: The Brave and the Bold, Star Wars: The Force Unleashed II, and Diablo III helped to make him one of the busiest voice actors in Hollywood.

Trivia: Began taking improv comedy classes at the age of 8 in a local teacher's backyard. Was voted Most Likely to Be Famous during her senior year of high school. At the age of 18, dropped out of college after one semester and moved to Los Angeles to pursue a career in comedy. Was a member of the renown sketch-comedy troupe The Groundlings. Auditioned to be a cast member of Saturday Night Live, but was rejected and offered a job as a writer for the show instead.

Trivia: Joined musical comedy company Venus Rising in 2001, performing in a number of productions. Joined improv comedy group Upstanding Citizens Brigade in 2004. Worked as a nanny alongside pursuing a career in acting. Co-created and co-starred in webseries Terrible Babysitters in 2013. As of 2019, has played Janet on NBC Comedy The Good Place. since its 2016 debut.

Trivia: Is of Jewish and Italian heritage. Worked as an intern at the Village Voice. Has performed at such events as the Montreal Just For Laughs Festival, the HBO Aspen Comedy Festival and the Las Vegas Comedy Festival. Performs with the all-female comedy troupe Variety Shac. Starred in the web series Making Friends and All My Exes. In 2012, began hosting the weekly podcast Call Chelsea Peretti.

Trivia: With her memorable performance as tough but sympathetic rebel teen Kim Kelly in the critically praised but criminally short-lived series Freaks and Geeks, actress Busy Philipps crafted one of the most compelling young characters in contemporary television. In addition to later serving as something of a life-support system for the rapidly expiring teen drama Dawson's Creek, Philipps has gone on to make a name for herself in such features as the Columbine-influenced Home Room and the 2004 comedy White Chicks as well. Born Elizabeth Jean Philipps in Oak Park, IL, the active youngster was quickly dubbed "Busy" for her seemingly boundless energy and sociability. A role as Wilber the Pig in a grade-school production of Charlotte's Web eventually lead to Philipps being voted Best Actress of her class in her senior yearbook. The ambitious screen prospect went on to take classes at the Acting Lab of Arizona, where she would write and produce a pair of successful plays. Philipps subsequently refined her skills by studying at England's Oxford School of Drama before making a name for herself in community theater around the Scottsdale area, with her first professional gig coming with a role as a real-life Barbie doll at Mattel's Toy Fair convention in New York. Philipps role in Freaks and Geeks did wonders for her exposure, regardless of the endearing show's remarkably short lifespan, and in the years that followed, she continued to impress in such features as Anatomy of a Hate Crime and Home Room. Many viewed Philipps' involvement with Dawson's Creek as something of a breath of fresh air for the somewhat stale series, with simultaneous appearances in the Freaks and Geeks follow-up series Undeclared proving a welcome opportunity to work with old friends. In 2004, Philipps took a supporting role opposite Jaime King in the Shawn and Marlon Wayans comedy White Chicks. In 2009 she was cast in the TV series Cougar Town, and in 2011 she appeared in the Sarah Jessica Parker vehicle I Don't Know How She Does It.

Trivia: Even those who don't know Kevin Michael Richardson's face will frequently remember his voice. The actor's unique baritone has made him a memorable presence in many projects, including several voices on the animated series Family Guy. A classically trained performer, Richardson was one of eight students selected for the 1982 National Foundation for the Arts program, leading to a full scholarship for Syracuse University. He would go on to become a successful actor and voice actor, wracking up a long list of roles on everything from Pokemon to The New Batman Adventures. Othyer shows featuring Richardson's distinctive voice include Transformers Prime, Ultimate Spider-Man, and Green Lantern: The Animated Series. Real-life voices Richardson has portrayed include Bob Hope (in a 2006 Malcolm in the Middle episode), Bill Cosby (a number of Family Guy episodes) and Plato (PBS's Adventures From the Book of Virtues, 1996-98).