Trivia: One of the salutary byproducts of the TV series Seinfeld is that it created a market in the '90s for sitcoms built around the comedy routines of young, hip New York comics. One of the best of these programs was Mad About You, created by and starring Manhattan-born Paul Reiser. Reiser and Seinfeld share more than a similarity of sitcoms; together with comedians Larry Miller and Mark Schiff, they comprise what has been unofficially dubbed the Four Funniest Men in the World Club, which has met for lunch each New Year's Day for the past several years. Reiser's credentials include a degree from S.U.N.Y.-Binghamton, a short stint as a health food distributor, and a 1982 film debut in Diner. Most of his film roles have been in comedies, though he was effectively cast as a greedy space traveler (who comes to a well-deserved bad end) in 1986's Aliens. Reiser has noted that his weekly series Mad About You, in which he co-starred with Helen Hunt, was based on his relationship with his wife, Paula. In 1995, Paul Reiser took a brief respite from Mad About You to star in the "single dad" comedy Bye Bye Love.As the new decade began, and Mad About You came to a close, Resier appeared in One Night at McCool's, and four years later realized a personal dream by co-starring with Peter Falk in The Thing About My Folks, a film Resier co-wrote as well. He was interviewed in The Aristocrats, and appeared as himself in Funny People. In 2011 he masterminded the very short-lived NBC sitcom The Paul Reiser Show.

Trivia: A precociously talented youngster, Helen Hunt was drawing paychecks as a television actress from the age of ten. Before she was 17, she had appeared as a regular on two series, Swiss Family Robinson (1975) and The Fitzpatricks (1977). Hunt proved she was more than just a workaday child actor with her starring performance in the fact-based 1981 TV movie The Miracle of Kathy Miller, in which she played a high school athlete who overcame severe mental and physical damage brought on by a highway accident. While she had been appearing in films as early as Rollercoaster in 1977, Hunt was never groomed as a star player, and it is possible that her resemblance to another child actress, Jodie Foster, held her back from more important roles.After taking on her first adult role in the 1982 sitcom It Takes Two, Hunt's film assignments improved, with sizable roles in Girls Just Want to Have Fun (1985), Peggy Sue Got Married (1986), Project X (1987), Next of Kin (1989), and The Waterdance (1991). She also gained a small measure of cult status by appearing in a brace of science fiction films, including Trancers II (1991) and Trancers III (1992). That same year, Hunt landed her longest-lasting acting assignment to date, as the co-star of the Paul Reiser-created comedy series Mad About You. During the show's seven-year run, she won both Emmy and Golden Globe awards for her portrayal of Jamie Buchman. In 1996, Hunt had her most successful film role to date in the blockbuster Twister. The following year, she topped that when she received a Best Actress Oscar for playing a caring waitress and single mother who befriends acerbic, obsessive-compulsive author Melvin Udall (Jack Nicholson, who also won an Oscar for his performance) in As Good As It Gets. After Mad About You ended in 1999, Hunt appeared in films by several veteran directors, including Robert Zemeckis (Cast Away [2000]), Robert Altman (Dr. T and The Women [2000]), and Woody Allen (The Curse of the Jade Scorpion [2001]). She starred in Life x 3 on Broadway in 2003.In 2005, Hunt joined the star-studded cast of HBO's two-part miniseries Empire Falls in the role of Janine, ex-wife of Miles (Ed Harris), the story's central character. The actress made her feature directorial debut in Then She Found Me (for which Hunt also starred, produced, and wrote the screenplay), an adaptation of Elinore Lipman's best-selling novel of the same name. The story follows a Philadelphia schoolteacher (Hunt) whose long-lost birth mother (Bette Miller) reappears at just as her daughter is careening into a midlife crisis. Hunt played a supportive mother in Soul Surfer (2011), an inspirational drama based on the true tale of a surfer who returned to the sport after tragically losing an arm. In 2012 she played a sex surrogate helping a man in an iron lung lose his virginity for director Ben Lewin in The Sessions, a part that earned her rave reviews and an Academy Award nomination for Best Supporting Actress.

Trivia: Raised outside of Chicago as the sixth of nine children, including older brother James, a founding member of the band Chicago. Left college in his junior year after seeing David Mamet's play, The American Buffalo, which inspired Pankow to enroll in the two-year training program at Chicago's St. Nicholas Theatre. Performed on Broadway (in his first stint) in Serious Money, The Iceman Cometh and as Mozart in Amadeus. Appeared in a numerous films of the late 1980s-early '90s, including To Live and Die in L.A., Talk Radio and Mortal Thoughts. Most recognized for his role as Ira Buchman, cousin of Paul Reiser's character, on the '90s NBC sitcom Mad About You. Returned to Broadway in the 2000s, performing in Twelve Angry Men, The Prime of Miss Jean Brodie and Cymbeline. Took over the role of Merc Lapidus (from Thomas Haden Church) in 2011 on the Showtime/BBC show Episodes.

Trivia: Made his acting debut at the age of 2, chasing golf balls in a commercial for Security Pacific Bank. Graduated early from high school at the age of 16. Is an accomplished jazz and classical pianist who composes both solo piano pieces and electronic songs, and also plays violin. Frequently volunteers with AIDS-related charities, including The Elizabeth Glaser Pediatric AIDS Foundation and Camp Heartland, a camp for children with AIDS and their families.

Trivia: Educated at Roosevelt University, bearded, booming-voiced Louis Zorich has been a working actor for nearly 50 years. Zorich made his off-Broadway debut in a revival of Pirandello's Six Characters in Search of an Author, and has appeared on Broadway in Becket, Moby Dick, Hadrian VII, and Moonchildren. He also appeared as Ben in Dustin Hoffman's 1984 staging of Death of a Salesman, repeating this role in the 1985 film version. On television, Zorich has been seen as Jules Berger in Brooklyn Bridge (1991) and as Paul Reiser's father in Mad About You (which ran from 1992 to 1999), and heard in innumerable commercial voice-overs. Louis Zorich is the husband of Oscar-winning actress Olympia Dukakis.

Trivia: Mare Winningham is a critically acclaimed performer on stage, television, and occasionally feature films. She began her career performing a song on TV's notorious Gong Show. While playing Maria in a high school production of The Sound of Music, opposite classmate Kevin Spacey, Winningham was spotted by Hollywood agent Meyer Mishkin who landed her a role in the short-lived TV Western series The Young Pioneers in 1978. This led to her first TV movie, Special Olympics. For her role as an independent-minded farmer's daughter in 1980's Amber Waves, she won an Emmy. That year, Winningham made her feature-film debut starring opposite Paul Simon in Robert M. Young's One-Trick Pony. She fared better in her next film, Threshold (1981), where she played the recipient of an artificial heart. Winningham then went on to play a number of supporting roles and the occasional lead in a series of unremarkable films. She continues to fare much better on television, where she has appeared in popular films such as The Thorn Birds (1983) and Helen Keller: The Miracle Continues (1984). She was part of the ensemble in the Gen X touchstone St. Elmo's Fire in 1985 and went on to appear in Shy People, Miracle Mile, the Tom Hanks with a dog vehicle Turner and Hooch, and Wyatt Earp. She earned long-deserved award recognition in 1995 for playing a successful singer struggling with her drug-addicted sister in Georgia. Her work in that film garnered her an Oscar nomination Best Supporting Actress, and she won that award at that year's Independent Spirit Awards. She had a recurring role on the hit medical drama ER at the close of the '90s. As the 21st century began she maintained her status as a first-class character actress appearing in a variety of projects such as Snap Decision, The Adventures of Ociee Nash, and Dandelion. She enjoyed a recurring role on Grey's Anatomy, but she found even greater small screen success with back to back Emmy nominations for Best Supporting actress in a movie or miniseries in 2011 and 2012 with her work in Mildred Pierce and Hatfields & McCoys.

Trivia: Supporting actress, onscreen from the '70s.

Trivia: Started her professional acting career in 1974.At the start of her career, learned to type to work in offices while also auditioning in New York.In 2008, was awarded the School of Theatre Distinguished Alumni Award by the Boston University College of Fine Arts.Has played a teacher in multiple projects, including Lean on Me (1989), If Looks Could Kill (1991), Curb Your Enthusiasm and Brooklyn Nine-Nine.In 2016, was nominated for the Independent Spirit Award for Best Supporting Female for her work in the film H. (2014).